[HTML][HTML] Identification of mobile genetic elements with geNomad

AP Camargo, S Roux, F Schulz, M Babinski, Y Xu… - Nature …, 2023 - nature.com
Identifying and characterizing mobile genetic elements in sequencing data is essential for
understanding their diversity, ecology, biotechnological applications and impact on public …

<? mode longmeta?> IMG/PR: a database of plasmids from genomes and metagenomes with rich annotations and metadata

AP Camargo, L Call, S Roux, S Nayfach… - Nucleic acids …, 2024 - academic.oup.com
Plasmids are mobile genetic elements found in many clades of Archaea and Bacteria. They
drive horizontal gene transfer, impacting ecological and evolutionary processes within …

[HTML][HTML] Insights into the circular: The cryptic plasmidome and its derived antibiotic resistome in the urban water systems

Z Yu, W He, F Klincke, JS Madsen, W Kot… - Environment …, 2024 - Elsevier
Plasmids have been a concern in the dissemination and evolution of antibiotic resistance in
the environment. In this study, we investigated the total pool of plasmids (plasmidome) and …

[HTML][HTML] Tandem repeats in giant archaeal Borg elements undergo rapid evolution and create new intrinsically disordered regions in proteins

MC Schoelmerich, R Sachdeva, J West-Roberts… - PLoS …, 2023 - journals.plos.org
Borgs are huge, linear extrachromosomal elements associated with anaerobic methane-
oxidizing archaea. Striking features of Borg genomes are pervasive tandem direct repeat …

[HTML][HTML] Characterizing conjugative plasmids from an antibiotic-resistant dataset for use as broad-host delivery vectors

HG Loyola Irizarry, IL Brito - Frontiers in Microbiology, 2023 - frontiersin.org
Human microbiome engineering is increasingly proposed as a way to modulate health
outcomes. However, one of the current limitations to engineering microbial communities in …

[HTML][HTML] Mutation-induced infections of phage-plasmids

X Shan, RE Szabo, OX Cordero - Nature Communications, 2023 - nature.com
Phage-plasmids are extra-chromosomal elements that act both as plasmids and as phages,
whose eco-evolutionary dynamics remain poorly constrained. Here, we show that …

[HTML][HTML] Diversity and Ecology of Caudoviricetes Phages with Genome Terminal Repeats in Fecal Metagenomes from Four Dutch Cohorts

A Gulyaeva, S Garmaeva, A Kurilshikov, A Vich Vila… - Viruses, 2022 - mdpi.com
The human gut harbors numerous viruses infecting the human host, microbes, and other
inhabitants of the gastrointestinal tract. Most of these viruses remain undiscovered, and their …

Borg tandem repeats undergo rapid evolution and are under strong selection to create new intrinsically disordered regions in proteins

MC Schoelmerich, R Sachdeva, L Waldburger… - bioRxiv, 2022 - biorxiv.org
Borgs are huge, linear extrachromosomal elements associated with anaerobic methane-
oxidizing archaea. Striking features of Borg genomes are pervasive tandem direct repeat …

The skin microbiome in health and atopic dermatitis

S Saheb Kashaf - 2023 - repository.cam.ac.uk
The skin, as the body's outermost layer of cells, plays a crucial dual role in protecting against
foreign pathogens while providing a habitat for commensal microbes. Despite the skin's …

Bioinformatic tool development and application to the human gut microbiome

A Chklovski - 2024 - eprints.qut.edu.au
Metagenomic shotgun sequencing has revolutionized the study of microbiology, However,
assessing metagenome-assembled genome (MAG) quality and identifying mobile genetic …