Protein data bank: a comprehensive review of 3D structure holdings and worldwide utilization by researchers, educators, and students
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB),
funded by the United States National Science Foundation, National Institutes of Health, and …
funded by the United States National Science Foundation, National Institutes of Health, and …
The HADDOCK2. 4 web server for integrative modeling of biomolecular complexes
Interactions between macromolecules, such as proteins and nucleic acids, are essential for
cellular functions. Experimental methods can fail to provide all the information required to …
cellular functions. Experimental methods can fail to provide all the information required to …
Electron microscopy holdings of the Protein Data Bank: the impact of the resolution revolution, new validation tools, and implications for the future
As a discipline, structural biology has been transformed by the three-dimensional electron
microscopy (3DEM)“Resolution Revolution” made possible by convergence of robust cryo …
microscopy (3DEM)“Resolution Revolution” made possible by convergence of robust cryo …
Making fluorescence-based integrative structures and associated kinetic information accessible
CA Hanke, JD Westbrook, BM Webb, TO Peulen… - Nature …, 2024 - nature.com
In integrative structure modeling ap proaches, data from different experimental and
theoretical techniques are combined to maximally utilize method-specific advantages and …
theoretical techniques are combined to maximally utilize method-specific advantages and …
[HTML][HTML] Transglutaminase 2 has higher affinity for relaxed than for stretched fibronectin fibers
Abstract Transglutaminase 2 (TG2) plays a vital role in stabilizing extracellular matrix (ECM)
proteins through enzymatic crosslinking during tissue growth, repair, and inflammation. TG2 …
proteins through enzymatic crosslinking during tissue growth, repair, and inflammation. TG2 …
RCSB Protein Data bank: Tools for visualizing and understanding biological macromolecules in 3D
Now in its 52nd year of continuous operations, the Protein Data Bank (PDB) is the premiere
open‐access global archive housing three‐dimensional (3D) biomolecular structure data. It …
open‐access global archive housing three‐dimensional (3D) biomolecular structure data. It …
[HTML][HTML] Sharing begins at home: how continuous and ubiquitous FAIRness can enhance research productivity and data reuse
The broad sharing of research data is widely viewed as critical for the speed, quality,
accessibility, and integrity of science. Despite increasing efforts to encourage data sharing …
accessibility, and integrity of science. Despite increasing efforts to encourage data sharing …
Overcoming challenges in structural biology with integrative approaches and nanobody-derived technologies
M Condeminas, MJ Macias - Current Opinion in Structural Biology, 2024 - Elsevier
A full understanding of protein structure is key to unraveling how these systems work, how
mutations affect their function, and discovering new hotspots for drug discovery. Research …
mutations affect their function, and discovering new hotspots for drug discovery. Research …
A new twist on PIFE: photoisomerisation-related fluorescence enhancement
PIFE was first used as an acronym for protein-induced fluorescence enhancement, which
refers to the increase in fluorescence observed upon the interaction of a fluorophore, such …
refers to the increase in fluorescence observed upon the interaction of a fluorophore, such …
Integration of nanometer-range label-to-label distances and their distributions into modelling approaches
G Jeschke - Biomolecules, 2022 - mdpi.com
Labelling techniques such as electron paramagnetic resonance spectroscopy and single-
molecule fluorescence resonance energy transfer, allow access to distances in the range of …
molecule fluorescence resonance energy transfer, allow access to distances in the range of …