The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

K Dheda, T Gumbo, G Maartens, KE Dooley… - The lancet Respiratory …, 2017 - thelancet.com
Global tuberculosis incidence has declined marginally over the past decade, and
tuberculosis remains out of control in several parts of the world including Africa and Asia …

Global control of tuberculosis: from extensively drug-resistant to untreatable tuberculosis

K Dheda, T Gumbo, NR Gandhi, M Murray… - The lancet Respiratory …, 2014 - thelancet.com
Extensively drug-resistant tuberculosis is a burgeoning global health crisis mainly affecting
economically active young adults, and has high mortality irrespective of HIV status. In some …

Nurses' lifestyle behaviours, health priorities and barriers to living a healthy lifestyle: a qualitative descriptive study

LP Phiri, CE Draper, EV Lambert, TL Kolbe-Alexander - BMC nursing, 2014 - Springer
Background Nurses have an increased risk for non-communicable diseases (NCDs), along
with a high prevalence of obesity, poor eating habits and insufficient physical activity. The …

Screening for HIV-associated tuberculosis and rifampicin resistance before antiretroviral therapy using the Xpert MTB/RIF assay: a prospective study

SD Lawn, SV Brooks, K Kranzer, MP Nicol… - PLoS …, 2011 - journals.plos.org
Background The World Health Organization has endorsed the Xpert MTB/RIF assay for
investigation of patients suspected of having tuberculosis (TB). However, its utility for routine …

Drug-penetration gradients associated with acquired drug resistance in patients with tuberculosis

K Dheda, L Lenders, G Magombedze… - American journal of …, 2018 - atsjournals.org
Rationale: Acquired resistance is an important driver of multidrug-resistant tuberculosis (TB),
even with good treatment adherence. However, exactly what initiates the resistance and …

Screening outcomes following implementation of digital breast tomosynthesis in a general-population screening program

AM McCarthy, D Kontos, M Synnestvedt… - Journal of the …, 2014 - academic.oup.com
Background Early data on breast cancer screening utilizing digital breast tomosynthesis
(DBT) combined with digital mammography (DM) have shown improvements in false …

Tuberculosis control in South Africa: successes, challenges and recommendations: tuberculosis control-Progress towards the Millennium Development Goals

GJ Churchyard, LD Mametja, L Mvusi… - South African Medical …, 2014 - journals.co.za
Tuberculosis (TB) remains a global health threat, and South Africa (SA) has one of the
world's worst TB epidemics driven by HIV. Among the 22 countries with the highest burden …

Surgical face masks worn by patients with multidrug-resistant tuberculosis: impact on infectivity of air on a hospital ward

AS Dharmadhikari, M Mphahlele, A Stoltz… - American journal of …, 2012 - atsjournals.org
Rationale: Drug-resistant tuberculosis transmission in hospitals threatens staff and patient
health. Surgical face masks used by patients with tuberculosis (TB) are believed to reduce …

Outcomes, infectiousness, and transmission dynamics of patients with extensively drug-resistant tuberculosis and home-discharged patients with programmatically …

K Dheda, JD Limberis, E Pietersen… - The lancet Respiratory …, 2017 - thelancet.com
Background The emergence of programmatically incurable tuberculosis threatens to
destabilise control efforts. The aim of this study was to collect prospective patient-level data …

[HTML][HTML] Global occupational health: current challenges and the need for urgent action

RG Lucchini, L London - Annals of Global health, 2014 - Elsevier
Background Global occupational health and safety (OHS) is strictly linked to the dynamics of
economic globalization. As the global market is increasing, the gap between developed and …