Functions of S100 proteins

R Donato, BR cannon, G Sorci, F Riuzzi… - Current molecular …, 2013 - ingentaconnect.com
The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …

RAGE regulation and signaling in inflammation and beyond

K Kierdorf, G Fritz - Journal of leukocyte biology, 2013 - academic.oup.com
ABSTRACT RAGE is a key molecule in the onset and sustainment of the inflammatory
response. New studies indicate that RAGE might represent a new link between the innate …

[HTML][HTML] S100B's double life: intracellular regulator and extracellular signal

R Donato, G Sorci, F Riuzzi, C Arcuri, R Bianchi… - … et Biophysica Acta (BBA …, 2009 - Elsevier
The Ca2+-binding protein of the EF-hand type, S100B, exerts both intracellular and
extracellular functions. Recent studies have provided more detailed information concerning …

The S100B protein in biological fluids: more than a lifelong biomarker of brain distress

F Michetti, V Corvino, MC Geloso… - Journal of …, 2012 - Wiley Online Library
J. Neurochem.(2012) 120, 644–659. Abstract S100B is a calcium‐binding protein
concentrated in glial cells, although it has also been detected in definite extra‐neural cell …

Biological and methodological features of the measurement of S100B, a putative marker of brain injury

CA Gonçalves, MC Leite, P Nardin - Clinical biochemistry, 2008 - Elsevier
The S100B astroglial protein is widely used as a parameter of glial activation and/or death in
several conditions of brain injury. Cerebrospinal fluid and serum S100B variations have …

Current status of fluid biomarkers in mild traumatic brain injury

JR Kulbe, JW Geddes - Experimental neurology, 2016 - Elsevier
Mild traumatic brain injury (mTBI) affects millions of people annually and is difficult to
diagnose. Mild injury is insensitive to conventional imaging techniques and diagnoses are …

A simple, sensitive and widely applicable ELISA for S100B: methodological features of the measurement of this glial protein

MC Leite, F Galland, G Brolese, MC Guerra… - Journal of Neuroscience …, 2008 - Elsevier
S100B expression, particularly extracellular S100B, is used as a parameter of glial activation
and/or death in several situations of brain injury. Several immunoassays for S100B …

S100B Interaction With the Receptor for Advanced Glycation End Products (RAGE) A Novel Receptor-Mediated Mechanism for Myocyte Apoptosis Postinfarction

JN Tsoporis, S Izhar, H Leong-Poi… - Circulation …, 2010 - Am Heart Assoc
Rationale: Post–myocardial infarction ventricular remodeling is associated with the
expression of a variety of factors including S100B that can potentially modulate myocyte …

S100 proteins in cardiovascular diseases

Y Zhou, Y Zha, Y Yang, T Ma, H Li, J Liang - Molecular Medicine, 2023 - Springer
Cardiovascular diseases have become a serious threat to human health and life worldwide
and have the highest fatality rate. Therefore, the prevention and treatment of cardiovascular …

S100B serum levels predict treatment response in patients with melancholic depression

O Ambrée, V Bergink, L Grosse… - International Journal …, 2016 - academic.oup.com
Background: There is an ongoing search for biomarkers in psychiatry, for example, as
diagnostic tools or predictors of treatment response. The neurotrophic factor S100 calcium …