YAP, TAZ, and Hippo-Dysregulating Fusion Proteins in Cancer

JH Driskill, JK Dermawan… - Annual Review of …, 2024 - annualreviews.org
Gene fusions are well-known drivers of cancer and are potent targets for molecular therapy.
An emerging spectrum of human tumors harbors recurrent and pathognomonic gene fusions …

The impact of SETBP1 mutations in neurological diseases and cancer

N Kohyanagi, T Ohama - Genes to Cells, 2023 - Wiley Online Library
SE translocation (SET) is a cancer‐promoting factor whose expression is upregulated in
many cancers. High SET expression positively correlates with a poor cancer prognosis …

Predictors of postoperative seizure outcome in supratentorial meningioma

R Gadot, AB Khan, R Patel, E Goethe, A Shetty… - Journal of …, 2021 - thejns.org
OBJECTIVE Meningiomas are the most common primary intracranial tumor. Seizures are
common sequelae of meningioma development. Meningioma patients with seizures can be …

Racial and socioeconomic disparities in patients with meningioma: a retrospective cohort study

HN Jackson, CC Hadley, AB Khan, R Gadot… - …, 2022 - journals.lww.com
BACKGROUND: Meningiomas are the most common intracranial neoplasms. Although
genomic analysis has helped elucidate differences in survival, there is evidence that racial …

Gene transcript fusions are associated with clinical outcomes and molecular groups of meningiomas

N Zakimi, MP Nguyen, DR Raleigh - Acta Neuropathologica, 2024 - Springer
The discovery of molecular groups of meningiomas that are associated with distinct
biological drivers, therapeutic vulnerabilities, and clinical outcomes provides a framework for …

Construction of a Cuproptosis-Related Gene Signature for Predicting Prognosis in Gastric Cancer

Y Hu, Y Du, Z Qiu, P Bai, Z Bai, C Zhu, J Wang… - Biochemical …, 2024 - Springer
This study aimed to develop and validate a cuproptosis-related gene signature for the
prognosis of gastric cancer. The data in TCGA GC TPM format from UCSC were extracted for …

Integrated clinical genomic analysis reveals xenobiotic metabolic genes are downregulated in meningiomas of current smokers

AB Khan, R Patel, MF McDonald, E Goethe… - Journal of Neuro …, 2023 - Springer
Introduction Meningiomas are the most common primary intracranial tumor. Recently,
various genetic classification systems for meningioma have been described. We sought to …

Molecular Biology and Genetics of Meningiomas: Classification and Diagnostic Methods

L Bertero, F Sahm, RM Di Crescenzo - Meningiomas: From Pathology to …, 2024 - Springer
Meningioma diagnosis is currently based on the criteria established by the latest WHO
Classification of Central Nervous System Tumours, published in 2021. Histopathological …