Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …

Amongst the lysosomal cysteine cathepsin family of proteases, cathepsin S (CTSS) holds
particular interest due to distinctive properties including a normal restricted expression …

In December 2019, the first cases of infection with a novel coronavirus, SARS-CoV-2, were
diagnosed. Currently, there is no effective antiviral treatment for COVID-19. To address this …

Objective—Coronary artery thrombosis can occur in the absence of plaque rupture because
of superficial erosion. Erosion-prone atheromata associate with more neutrophil …

Real‐time optical imaging of immune cells can contribute to understanding their
pathophysiological roles, which still remains challenging. Current sensitive …

Imaging to evaluate tumor‐associated neutrophils (TANs) is imperative for cancer
immunotherapy but remains challenging. We herein report an activatable semiconducting …

We are in the midst of a technological revolution that is providing new insights into human
biology and cancer. In this era of big data, we are amassing large amounts of information …

Proteases play critical roles in virtually all biological processes, including proliferation, cell
death and survival, protein turnover, and migration. However, when dysregulated, these …

Human breath contains many volatile metabolites. However, few breath tests are currently
used in the clinic to monitor disease due to bottlenecks in biomarker identification. Here we …

Activated neutrophils can undergo a mode of regulated cell death, called NET osis, that
results in the extrusion of chromatin into the extracellular space, thereby acting as …