Metagenomics-enabled microbial surveillance

KKK Ko, KR Chng, N Nagarajan - Nature Microbiology, 2022 - nature.com
Lessons learnt from the COVID-19 pandemic include increased awareness of the potential
for zoonoses and emerging infectious diseases that can adversely affect human health …

Advances and challenges in metatranscriptomic analysis

M Shakya, CC Lo, PSG Chain - Frontiers in genetics, 2019 - frontiersin.org
Sequencing-based analyses of microbiomes have traditionally focused on addressing the
question of community membership and profiling taxonomic abundance through amplicon …

The use of next generation sequencing for improving food safety: Translation into practice

B Jagadeesan, P Gerner-Smidt, MW Allard, S Leuillet… - Food …, 2019 - Elsevier
Abstract Next Generation Sequencing (NGS) combined with powerful bioinformatic
approaches are revolutionising food microbiology. Whole genome sequencing (WGS) of …

Advances in understanding the human urinary microbiome and its potential role in urinary tract infection

ML Neugent, NV Hulyalkar, VH Nguyen, PE Zimmern… - MBio, 2020 - Am Soc Microbiol
Recent advances in the analysis of microbial communities colonizing the human body have
identified a resident microbial community in the human urinary tract (UT). Compared to many …

Higher abundance of core antimicrobial resistant genes in effluent from wastewater treatment plants

S Raza, H Shin, HG Hur, T Unno - Water research, 2022 - Elsevier
Wastewater treatment plants (WWTPs) receive sewage water from a variety of sources,
including livestock farms, hospitals, industries, and households, that contain antimicrobial …

Next generation sequencing and bioinformatics methodologies for infectious disease research and public health: approaches, applications, and considerations for …

I Maljkovic Berry, MC Melendrez… - The Journal of …, 2020 - academic.oup.com
Next generation sequencing (NGS) combined with bioinformatics has successfully been
used in a vast array of analyses for infectious disease research of public health relevance …

Sunbeam: an extensible pipeline for analyzing metagenomic sequencing experiments

EL Clarke, LJ Taylor, C Zhao, A Connell, JJ Lee, B Fett… - Microbiome, 2019 - Springer
Background Analysis of mixed microbial communities using metagenomic sequencing
experiments requires multiple preprocessing and analytical steps to interpret the microbial …

A review of bioinformatics tools for bio-prospecting from metagenomic sequence data

DD Roumpeka, RJ Wallace, F Escalettes… - Frontiers in …, 2017 - frontiersin.org
The microbiome can be defined as the community of microorganisms that live in a particular
environment. Metagenomics is the practice of sequencing DNA from the genomes of all …

Characterizing phage genomes for therapeutic applications

CW Philipson, LJ Voegtly, MR Lueder, KA Long… - Viruses, 2018 - mdpi.com
Multi-drug resistance is increasing at alarming rates. The efficacy of phage therapy, treating
bacterial infections with bacteriophages alone or in combination with traditional antibiotics …

An integrated pipeline for annotation and visualization of metagenomic contigs

X Dong, M Strous - Frontiers in genetics, 2019 - frontiersin.org
Here, we describe MetaErg, a standalone and fully automated metagenome and
metaproteome annotation pipeline. Annotation of metagenomes is challenging. First …