Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity

K Gupta, G Kaur, T Pathak, I Banerjee - Gene, 2022 - Elsevier
The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …

Vitamin D and COVID‐19—revisited

S Subramanian, G Griffin, M Hewison… - Journal of internal …, 2022 - Wiley Online Library
Vitamin D, when activated to 1, 25‐dihydroxyvitamin D, is a steroid hormone that induces
responses in several hundred genes, including many involved in immune responses to …

Vitamin D deficiency and vitamin D receptor FokI polymorphism as risk factors for COVID-19

NMS Zeidan, HMAE Lateef, DM Selim, SA Razek… - Pediatric …, 2023 - nature.com
Background Given the sparse data on vitamin D status in pediatric COVID-19, we
investigated whether vitamin D deficiency could be a risk factor for susceptibility to COVID …

[HTML][HTML] The association of ACE1, ACE2, TMPRSS2, IFITM3 and VDR polymorphisms with COVID-19 severity: A systematic review and meta-analysis

Z Dobrijevic, D Robajac, N Gligorijevic, M Šunderic… - EXCLI …, 2022 - ncbi.nlm.nih.gov
Genes involved in the regulation of viral recognition and its entry into a host cell have been
identified as candidates for genetic association studies on COVID-19 severity. Published …

Angiotensin-Converting Enzyme (ACE) level, but not ACE gene polymorphism, is associated with prognosis of COVID-19 infection: Implications for diabetes and …

O Elbasan, F Bayram, CD Yazan, T Apaydın… - PloS one, 2023 - journals.plos.org
Background The renin-angiotensin-aldosterone system was shown to be activated in severe
COVID-19 infection. We aimed to investigate the relationship between angiotensin …

Genetic variations of the vitamin D metabolic pathway and COVID-19 susceptibility and severity: current understanding and existing evidence

N Charoenngam, A Jaroenlapnopparat, SK Mettler… - Biomedicines, 2023 - mdpi.com
The immunomodulatory and metabolic effects of vitamin D receptor (VDR) activation have
been considered beneficial in mitigating the susceptibility and severity of COVID-19 …

Role of FokI rs2228570 and Tru9I rs757343 polymorphisms in the mortality of patients infected with different variants of SARS-CoV-2

HRS Shawi, E Anvari, A Fateh - Archives of Medical Research, 2023 - Elsevier
Background and aim Low vitamin D levels are associated with the severity of coronavirus
disease 19 (COVID-19). Vitamin D receptor gene polymorphisms, such as Tru9I rs757343 …

Association of ApaI rs7975232 and BsmI rs1544410 in clinical outcomes of COVID-19 patients according to different SARS-CoV-2 variants

ANR Al-Gharrawi, E Anvari, A Fateh - Scientific Reports, 2023 - nature.com
A growing body of research has shown how important vitamin D is in the prognosis of
coronavirus disease 19 (COVID-19). The vitamin D receptor is necessary for vitamin D to …

Vitamin D and SARS‐CoV‐2

SL Feentved Ødum… - Basic & Clinical …, 2023 - Wiley Online Library
The single‐stranded RNA virus, SARS‐CoV‐2, causing the COVID‐19 pandemic, has
severely impacted daily life globally. It has been suggested to supplement the general …

Exploring the Influence of VDR Genetic Variants TaqI, ApaI, and FokI on COVID-19 Severity and Long-COVID-19 Symptoms

G Alhammadin, Y Jarrar, A Madani, SJ Lee - Journal of Personalized …, 2023 - mdpi.com
There is increasing evidence regarding the importance of vitamin D in the prognosis of
coronavirus disease 2019 (COVID-19). Genetic variants in the vitamin D receptor (VDR) …