A materials-science perspective on tackling COVID-19

Z Tang, N Kong, X Zhang, Y Liu, P Hu, S Mou… - Nature Reviews …, 2020 - nature.com
The ongoing SARS-CoV-2 pandemic highlights the importance of materials science in
providing tools and technologies for antiviral research and treatment development. In this …

Biomedical applications of biodegradable polymers

BD Ulery, LS Nair, CT Laurencin - Journal of polymer science …, 2011 - Wiley Online Library
Utilization of polymers as biomaterials has greatly impacted the advancement of modern
medicine. Specifically, polymeric biomaterials that are biodegradable provide the significant …

Bioresponsive drug delivery systems for the treatment of inflammatory diseases

Y Dou, C Li, L Li, J Guo, J Zhang - Journal of Controlled Release, 2020 - Elsevier
Inflammation is intimately related to the pathogenesis of numerous acute and chronic
diseases like cardiovascular disease, inflammatory bowel disease, rheumatoid arthritis, and …

Zeolitic imidazolate framework-8 as efficient pH-sensitive drug delivery vehicle

CY Sun, C Qin, XL Wang, GS Yang, KZ Shao… - Dalton …, 2012 - pubs.rsc.org
Zeolitic Imidazolate Framework-8 (ZIF-8), for the first time for ZIFs, exhibits a remarkable
capacity for the anticancer drug 5-fluorouracil (5-FU), around 660 mg of 5-FU/g of ZIF-8, and …

Lymph node targeting strategies to improve vaccination efficacy

H Jiang, Q Wang, X Sun - Journal of Controlled Release, 2017 - Elsevier
With the rapid development of nanotechnology as well as growing interest in
immunotherapy, a great number of vaccine delivery vehicles have been explored in order to …

Responsive polymers in controlled drug delivery

AK Bajpai, SK Shukla, S Bhanu, S Kankane - Progress in Polymer Science, 2008 - Elsevier
This article reviews the state-of-the art in responsive polymer systems for controlled drug
delivery applications. The paper describes different types of stimuli-sensitive systems and …

[HTML][HTML] Microencapsulation: A promising technique for controlled drug delivery

MN Singh, KSY Hemant, M Ram… - Research in …, 2010 - ncbi.nlm.nih.gov
Microparticles offer various significant advantages as drug delivery systems, including:(i) an
effective protection of the encapsulated active agent against (eg enzymatic) degradation,(ii) …

Exploiting lymphatic transport and complement activation in nanoparticle vaccines

ST Reddy, AJ Van Der Vlies, E Simeoni, V Angeli… - Nature …, 2007 - nature.com
Abstract Antigen targeting,,,, and adjuvancy schemes, that respectively facilitate delivery of
antigen to dendritic cells and elicit their activation have been explored in vaccine …

Polymer microspheres for controlled drug release

S Freiberg, XX Zhu - International journal of pharmaceutics, 2004 - Elsevier
Polymer microspheres can be employed to deliver medication in a rate-controlled and
sometimes targeted manner. Medication is released from a microsphere by drug leaching …

In vivo targeting of dendritic cells in lymph nodes with poly (propylene sulfide) nanoparticles

ST Reddy, A Rehor, HG Schmoekel, JA Hubbell… - Journal of Controlled …, 2006 - Elsevier
Delivery of biodegradable nanoparticles to antigen-presenting cells (APCs), specifically
dendritic cells (DCs), has potential for immunotherapy. This study investigates the delivery of …