Emerging role of exosomes in cancer progression and tumor microenvironment remodeling

MDA Paskeh, M Entezari, S Mirzaei, A Zabolian… - Journal of hematology & …, 2022 - Springer
Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …

The role of extracellular vesicles in the hallmarks of cancer and drug resistance

CPR Xavier, HR Caires, MAG Barbosa, R Bergantim… - Cells, 2020 - mdpi.com
Extracellular vesicles (EVs) mediate intercellular signaling and communication, allowing the
intercellular exchange of proteins, lipids, and genetic material. Their recognized role in the …

Mesothelial-to-mesenchymal transition and exosomes in peritoneal metastasis of ovarian cancer

L Pascual-Antón, B Cardeñes… - International journal of …, 2021 - mdpi.com
Most patients with ovarian cancer (OvCA) present peritoneal disseminated disease at the
time of diagnosis. During peritoneal metastasis, cancer cells detach from the primary tumor …

Revolutionizing cancer therapy: nanoformulation of miRNA-34–enhancing delivery and efficacy for various cancer immunotherapies: a review

MP Fawzy, HAFM Hassan, NK Sedky, MS Nafie… - Nanoscale …, 2024 - pubs.rsc.org
Despite recent advancements in cancer therapies, challenges such as severe toxic effects,
non-selective targeting, resistance to chemotherapy and radiotherapy, and recurrence of …

Exosomes from cervical cancer cells facilitate pro-angiogenic endothelial reconditioning through transfer of Hedgehog–GLI signaling components

A Bhat, J Yadav, K Thakur, N Aggarwal, T Tripathi… - Cancer Cell …, 2021 - Springer
Background Angiogenic switch is a hallmark feature of transition from low-grade to high-
grade cervical intraepithelial neoplasia (CIN) in cervical cancer progression. Therefore …

Docosahexaenoic acid reverses the promoting effects of breast tumor cell-derived exosomes on endothelial cell migration and angiogenesis

P Ghaffari-Makhmalbaf, M Sayyad, K Pakravan… - Life sciences, 2021 - Elsevier
Aim As a natural compound, docosahexaenoic acid (DHA) exerts anti-cancer and anti-
angiogenesis functions through exosomes; however, little is known about the molecular …

Unraveling the extracellular vesicle network: insights into ovarian cancer metastasis and chemoresistance

W Dai, J Zhou, T Chen - Molecular Cancer, 2024 - Springer
Ovarian cancer (OC) is one of the most prevalent and lethal gynecological malignancies,
with high mortality primarily due to its aggressive nature, frequent metastasis, and resistance …

Exosomes from chondrocytes overexpressing miR-214-3p facilitate M2 macrophage polarization and angiogenesis to relieve Legg Calvé-Perthes disease

X Lan, R Yu, J Xu, X Jiang - Cytokine, 2023 - Elsevier
Abstract Objective Legg-Calvé-Perthes disease (LCPD) is a partial or total necrosis of
femoral head bone caused by blood supply disorder and its etiology is not clear. Studies …

[HTML][HTML] The pluripotent role of exosomes in mediating non-coding RNA in ventricular remodeling after myocardial infarction

Z Qi, D Wu, M Li, Z Yan, X Yang, N Ji, Y Wang, J Zhang - Life sciences, 2020 - Elsevier
With the increase of an aging population and the rising incidence of cardiovascular
diseases, heart failure (HF) patients are on the rise every year. Myocardial infarction (MI) is …

The crosstalk between lung cancer cells and platelets promotes tumor angiogenesis in vivo and in vitro

B Li, T Zhu, X Wu, S Chen, C Lu, J Zhu, Q Li - Journal of Cancer Research …, 2023 - Springer
Purpose We previously showed that the crosstalk of H1975 cells and platelets (PLTs) may
promote tumor angiogenesis. This study aimed to determine whether other lung cell lines …