Challenges and opportunities in clinical diagnostic routine of envenomation using blood plasma proteomics

JS Cavalcante, DEG de Almeida, MS Moraes… - Toxins, 2023 - mdpi.com
Specific and sensitive tools for the diagnosis and monitoring of accidents by venomous
animals are urgently needed. Several diagnostic and monitoring assays have been …

[HTML][HTML] Impact of delayed PBMC processing on functional and genomic assays

PC Yi, L Zhuo, J Lin, C Chang, A Goddard… - Journal of Immunological …, 2023 - Elsevier
Peripheral blood mononuclear cells (PBMCs) are commonly isolated from whole blood
samples in clinical trials. Isolated PBMCs can be cryopreserved for use in downstream …

Use of RNA biomarkers in the antidoping field

F Loria, S Grabherr, T Kuuranne, N Leuenberger - Bioanalysis, 2024 - Taylor & Francis
There is growing evidence that various RNA molecules can serve as biomarkers for clinical
diagnoses. Over the last decade, the high specificities and sensitivities of RNA biomarkers …

Buffy coat processing impacts on monocytes' capacity to present lipid antigens

I Mondragão-Rodrigues, MF Macedo - Biomedicines, 2023 - mdpi.com
Buffy Coats, generated from a blood donor's whole blood bag unit, are commonly used in
biomedical research as a source of leukocytes due to the high number of cells that can be …

Impact on in-depth immunophenotyping of delay to peripheral blood processing

LE Higdon, S Scheiding, AM Kus, N Lim… - Clinical and …, 2024 - academic.oup.com
Peripheral blood mononuclear cell (PBMC) immunophenotyping is crucial in tracking
activation, disease state, and response to therapy in human subjects. Many studies require …

[HTML][HTML] Human blood cell transcriptomics unveils dynamic systemic immune modulation along colorectal cancer progression

A Martinez-Usatorre, L Ciarloni… - Journal for …, 2024 - pmc.ncbi.nlm.nih.gov
Background Colorectal cancer (CRC) is the second leading cause of cancer-related deaths
worldwide. CRC deaths can be reduced with prevention and early diagnosis. Circulating …

Effect of ORF7 of SARS‐CoV‐2 on the Chemotaxis of Monocytes and Neutrophils In Vitro

G Wang, J Guan, G Li, F Wu, Q Yang, C Huang… - Disease …, 2021 - Wiley Online Library
Coronavirus disease 2019 (COVID‐19) caused by the severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2) is currently the most significant public health threat worldwide …

Purpose, Partnership, and Possibilities: The Implementation of the Dog Aging Project Biobank

L Mouttham, MG Castelhano - Biomarker Insights, 2022 - journals.sagepub.com
Background: Biobanks have been supporting longitudinal prospective and retrospective
studies by providing standardized services for the acquisition, transport, processing, storage …