Comparative anatomy of the aldo–keto reductase superfamily

JM Jez, MJ Bennett, BP Schlegel, M Lewis… - Biochemical …, 1997 - portlandpress.com
The aldo–keto reductases metabolize a wide range of substrates and are potential drug
targets. This protein superfamily includes aldose reductases, aldehyde reductases …

Flavoenzymes: diverse catalysts with recurrent features

MW Fraaije, A Mattevi - Trends in biochemical sciences, 2000 - cell.com
Many biochemical processes exploit the extraordinary versatility of flavoenzymes and their
flavin cofactors. Flavoproteins are now known to have a variety of folding topologies but a …

1.8 and 1.9 Å resolution structures of the Penicillium amagasakiense and Aspergillus niger glucose oxidases as a basis for modelling substrate complexes

G Wohlfahrt, S Witt, J Hendle… - … Section D: Biological …, 1999 - journals.iucr.org
Glucose oxidase is a flavin-dependent enzyme which catalyses the oxidation of [beta]-d-
glucose by molecular oxygen to [bold delta]-gluconolactone and hydrogen peroxide. The …

Artificial ligand binding within the HIF2α PAS-B domain of the HIF2 transcription factor

TH Scheuermann, DR Tomchick… - Proceedings of the …, 2009 - National Acad Sciences
The hypoxia-inducible factor (HIF) basic helix–loop–helix Per-aryl hydrocarbon receptor
nuclear translocator (ARNT)-Sim (bHLH-PAS) transcription factors are master regulators of …

Cholesterol oxidase: sources, physical properties and analytical applications

J MacLachlan, ATL Wotherspoon, RO Ansell… - The Journal of steroid …, 2000 - Elsevier
Since Flegg (HM Flegg, An investigation of the determination of serum cholesterol by an
enzymatic method, Ann. Clin. Biochem. 10 (1973) 79–84) and Richmond (W. Richmond, The …

Mechanoregulatory Cholesterol Oxidase‐Functionalized Nanoscale Metal–Organic Framework Stimulates Pyroptosis and Reinvigorates T Cells

W Zhen, T Luo, Z Wang, X Jiang, E Yuan… - Small, 2023 - Wiley Online Library
Cancer cells alter mechanical tension in their cell membranes. New interventions to regulate
cell membrane tension present a potential strategy for cancer therapy. Herein, the increase …

Enzymology and molecular biology of aflatoxin biosynthesis

RE Minto, CA Townsend - Chemical reviews, 1997 - ACS Publications
Enzymology and Molecular Biology of Aflatoxin Biosynthesis | Chemical Reviews ACS ACS
Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications …

Crystal structure of D-amino acid oxidase: a case of active site mirror-image convergent evolution with flavocytochrome b2.

A Mattevi, MA Vanoni, F Todone… - Proceedings of the …, 1996 - National Acad Sciences
D-amino acid oxidase is the prototype of the FAD-dependent oxidases. It catalyses the
oxidation of D-amino acids to the corresponding alpha-ketoacids. The reducing equivalents …

Steroids in molecular recognition

P Wallimann, T Marti, A Fürer, F Diederich - Chemical reviews, 1997 - ACS Publications
Steroids are found in all eucaryotic organisms and display a great variety of different
biological functions. 1 The most frequent steroid is the highly lipophilic cholesterol (1, Figure …

Covalent attachment of flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) to enzymes: the current state of affairs

M Mewies, WS McIntire, NS Scrutton - Protein Science, 1998 - Wiley Online Library
The first identified covalent flavoprotein, a component of mammalian succinate
dehydrogenase, was reported 42 years ago. Since that time, more than 20 covalent …