Despite international efforts to 'roll back malaria'the 2008 World Malaria Report revealed the
disease still affects approximately 3 billion people in 109 countries; 45 within the WHO …

Ca2+-ATPases (pumps) are key actors in the regulation of Ca2+ in eukaryotic cells and are
thus essential to the correct functioning of the cell machinery. They have high affinity for …

The human malaria parasite Plasmodium vivax is responsible for 25–40% of the∼ 515
million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe …

Despite great international efforts, malaria still inflicts an enormous toll on human lives,
especially in Africa. Throughout history, antimalarial medicines have been one of the most …

Artemisinins are derived from extracts of sweet wormwood (Artemisia annua) and are well
established for the treatment of malaria, including highly drug-resistant strains. Their efficacy …

Artemisinin (ART)-based combination therapies (ACTs) are the first-line drugs—and often
the last treatments—that can effectively cure Plasmodium falciparum infections …

Artemisinin and its derivatives represent the most important and influential class of drugs in
the fight against malaria. Since the discovery of artemisinin in the early 1970s, the global …

Artemisinin derivatives are an essential component of treatment against multidrug-resistant
Plasmodium falciparum malaria. We aimed to investigate in-vitro resistance to artemisinin …

New drug development strategies are needed to combat antimicrobial resistance. The object
of this perspective is to highlight one such strategy: treating infections with sets of drugs …

Malaria has been a global epidemic health threat since ancient times. It still claims roughly
half a million lives every year in this century. Artemisinin and its derivatives, are frontline …