Once acquired, a fearful memory can persist for a lifetime. Although learned fear can be
extinguished, extinction memories are fragile. The resilience of fear memories to extinction …

Memory formation enables the retention of life experiences overtime. Based on previously
acquired information, organisms can anticipate future events and adjust their behaviors to …

Fear learning ensures survival through an expression of certain behavior as a conditioned
fear response. Fear memory is processed and stored in a fear memory circuit, including the …

Despite adolescence being a developmental window of vulnerability, up until very recently
there were surprisingly few studies on fear extinction during this period. Here we summarise …

Fear inhibition is markedly impaired in adolescent rodents and humans. The present
experiments investigated whether this impairment is critically determined by the animal's …

Explicit memory after anaesthesia has gained considerable attention because of its negative
implications, while implicit memory, which is more elusive and lacks patients' explicit recall …

D‐cycloserine (DCS) is currently under clinical trials for a number of neuropsychiatric
conditions and has been found to augment fear extinction in rodents and exposure therapy …

The medial prefrontal cortex (mPFC) has been implicated in the processing of emotionally
significant stimuli, particularly the inhibition of inappropriate responses. We examined the …

It is generally believed that after memory consolidation, memory-encoding synaptic circuits
are persistently modified and become less plastic. This, however, may hinder the remaining …

Associative learning is encoded under anesthesia and involves the medial prefrontal cortex
(mPFC). Neuronal activity in mPFC increases in response to a conditioned stimulus (CS+) …