Recent advances in visible light-mediated chemical transformations of enaminones

Y Han, L Zhou, C Wang, S Feng, R Ma, JP Wan - Chinese Chemical Letters, 2024 - Elsevier
Enaminones, which possesses both the nucleophilic enamine as well as electrophilic enone
structures, are well known versatile building blocks in organic synthesis. Meanwhile, visible …

Recent advances in reactions using enaminone in water or aqueous medium

Z Wang, B Zhao, Y Liu, JP Wan - Advanced Synthesis & …, 2022 - Wiley Online Library
Enaminones have in the past decade received renewed interest in organic synthesis by
acting as highly versatile building blocks. Particularly, the featured amino and carbonyl …

Electrochemical enaminone C–H thiolation/C–N amination cascade for thiazole synthesis and its diastereoselective dearomatization

H Guo, Y Liu, C Wen, JP Wan - Green Chemistry, 2022 - pubs.rsc.org
An electrochemical method for the synthesis of 2-aminothiazoles via aryl ring construction
using enaminones and thioureas is reported. The cascade enamine C–H thiolation and C–N …

Visible light-induced recyclable gC 3 N 4 catalyzed thiocyanation of C (sp 2)–H bonds in sustainable solvents

FL Zeng, HL Zhu, XL Chen, LB Qu, B Yu - Green Chemistry, 2021 - pubs.rsc.org
A metal-free photocatalytic strategy for the preparation of thiocyanated heterocycles from
inexpensive NH4SCN has been developed using carbon nitride (g-C3N4) as a general …

Iodine-Promoted Thioylation and Dicarbonylation of Enaminone α-C Sites: Synthesis of Fully Substituted Thiazoles via C═ C Bond Cleavage

P Zhao, Y Zhou, C Wang, AX Wu - The Journal of Organic …, 2024 - ACS Publications
A novel iodine-promoted difunctionalization of α-C sites in enaminones was demonstrated
as a means of synthesizing a variety of fully substituted thiazoles by constructing C–C (CO) …

Recent progress of direct thiocyanation reactions

H Chen, X Shi, X Liu, L Zhao - Organic & Biomolecular Chemistry, 2022 - pubs.rsc.org
Thiocyanates are common in natural products, synthetic drugs and bioactive molecules.
Many thiocyanate derivatives show excellent antibacterial, antiparasitic and anticancer …

Supporting-electrolyte-free electrochemical [2+ 2+ 1] annulation of benzo [d] isothiazole 1, 1-dioxides, N-arylglycines and paraformaldehyde

HY Song, J Jiang, YH Song, MH Zhou, C Wu… - Chinese Chemical …, 2024 - Elsevier
The H-bond promoted electrochemical [2+ 2+ 1] annulation of benzo [d] isothiazole 1, 1-
dioxides, N-arylglycines and paraformaldehyde for the synthesis of various benzo [d] …

Photocatalytic C–H Thiocyanation of NH2-Enaminones and the Tunable Synthetic Routes to 2-Aminothiazoles and 2-Thiazolinones

J Zeng, JP Wan, Y Liu - The Journal of Organic Chemistry, 2022 - ACS Publications
Visible light photocatalytic reactions of NH2-enaminones and ammonium thiocyanate for
chemoselective α-C–H thiocyanation have been realized for the first time, providing a …

Visible-Light-Driven Multicomponent Cyclization by Trapping a 1,3-Vinylimine Ion Intermediate: A Direct Approach to Pyrimido[1,2-b]indazole Derivatives

X Geng, Z Xu, Y Cai, L Wang - Organic Letters, 2021 - ACS Publications
Here we develop a novel visible-light-driven three-component cyclization by trapping an 1, 3-
vinylimine ion intermediate for the direct synthesis of pyrimido [1, 2-b] indazole derivatives …

Rh (III)-catalyzed enaminone-directed C–H coupling with diazodicarbonyls for skeleton-divergent synthesis of isocoumarins and naphthalenes

W Wu, X Wu, S Fan, J Zhu - Organic Letters, 2022 - ACS Publications
Diversity-oriented synthesis is tremendously useful for expanding the explorable chemical
space but restricted by the limited available toolbox of skeleton-diversification chemistry. We …