Introduction Successful treatment of haematological malignancies is frequently complicated
by Invasive Aspergillosis (IA), a life-threatening fungal infection that occurs in at least 10% of …

The patient has achieved a morphologic complete remission with 2 cycles of induction
chemotherapy. An HLA-matched unrelated donor has been identified, and he is planned to …

Contemporary data on infections after intensive chemotherapy for acute myeloid leukemia
(AML) are scarce. Cladribine, high-dose cytarabine, G-CSF, and dose-escalated …

Acute leukaemic and autologous HCT patients with resolved neutropenic fever prior to count
recovery can have empiric therapy safely discontinued or de-escalated. There is an …

ABSTRACT Introduction Invasive fungal infections (IFIs) are associated with a high morbidity
and mortality and their incidence is rising. Posaconazole is a triazole antifungal drug that …

Several new antifungal agents have become available for primary fungal prophylaxis of
neutropenia fever in hematological malignancy patients. Our aim was to synthesize all …

In the attempt to establish definitions and provide shared approaches to breakthrough
invasive fungal diseases (br-IFD) in acute myeloid leukemia (AML) patients submitted to …

Acute leukemias are complex diseases to treat and have a high mortality rate. The
immunosuppression caused by chemotherapy also causes the patient to become …

Background Invasive fungal disease (IFD) is a major complication of acute leukemia, thus
primary antifungal prophylaxis (PAP) is recommended by guidelines. Nevertheless …

Posaconazole and voriconazole are commonly used for preventing invasive fungal disease
(IFD), but few studies compared posaconazole with voriconazole for primary antifungal …