Preparation and application of pH-responsive drug delivery systems

H Ding, P Tan, S Fu, X Tian, H Zhang, X Ma… - Journal of Controlled …, 2022 - Elsevier
Microenvironment-responsive drug delivery systems (DDSs) can achieve targeted drug
delivery, reduce drug side effects and improve drug efficacies. Among them, pH-responsive …

Recent advances in pH-or/and photo-responsive nanovehicles

Y Shin, P Husni, K Kang, D Lee, S Lee, E Lee, Y Youn… - Pharmaceutics, 2021 - mdpi.com
The combination of nanotechnology and chemotherapy has resulted in more effective drug
design via the development of nanomaterial-based drug delivery systems (DDSs) for tumor …

Iron oxide nanoparticles-loaded hydrogels for effective topical photothermal treatment of skin cancer

R Amatya, D Kim, KA Min, MC Shin - Journal of Pharmaceutical …, 2022 - Springer
Purpose A hydrogel containing dextran-coated iron oxide nanoparticles (DEX-IONP) was
developed, and its applicability in topical photothermal therapy (PTT) of skin cancer was …

Laser enhanced combinatorial chemo-photothermal therapy of green synthesis gold nanoparticles loaded with 6mercaptopurine on breast cancer model

AH Faid, SA Shouman, NA Thabet, YA Badr… - Journal of …, 2023 - Springer
Purpose We tend to evaluated a method for loading 6Mercaptopurine (6MP) on green
synthesized hybrid chitosan gold nanoparticles (AuNPs) forming 6MP-AuNPs …

In vitro and in Vivo evaluation of PEGylated starch-coated iron oxide nanoparticles for enhanced photothermal cancer therapy

R Amatya, S Hwang, T Park, KA Min, MC Shin - Pharmaceutics, 2021 - mdpi.com
Iron oxide nanoparticles (IONPs) possess versatile utility in cancer theranostics, thus, they
have drawn enormous interest in the cancer research field. Herein, we prepared …

Development and characterization of pH-responsive nanocarriers for chemo-photothermal combination therapy of acidic tumors

P Husni, Y Shin, H Jeon, ES Lee, YS Youn… - Journal of Controlled …, 2023 - Elsevier
The combination of photothermal therapy and chemotherapy has been considered a
promising strategy for improving the excellent antitumor activities of these treatments. In this …

Development of a pH-responsive polymer based on hyaluronic acid conjugated with imidazole and dodecylamine for nanomedicine delivery

SM Han, JC Kim, Y Shin, D Lee, T Sim, C Lim… - Macromolecular …, 2022 - Springer
Hyaluronic acid (HA) is being actively studied as a drug carrier due to its favorable
properties and functional groups for chemical modification. Despite its high functionality, p K …

Bio-responsive carriers for controlled delivery of doxorubicin to cancer cells

G Fundueanu, M Constantin, M Turtoi, SM Bucatariu… - Pharmaceutics, 2022 - mdpi.com
The cellular internalization of drug carriers occurs via different endocytic pathways that
ultimately involve the endosomes and the lysosomes, organelles where the pH value drops …

Highly red light-emitting erbium-and lutetium-doped core-shell upconverting nanoparticles surface-modified with PEG-folic acid/TCPP for suppressing cervical cancer …

K Lim, HK Kim, XT Le, NT Nguyen, ES Lee, KT Oh… - Pharmaceutics, 2020 - mdpi.com
Photodynamic therapy (PDT) combined with upconverting nanoparticles (UCNPs) are
viewed together as an effective method of ablating tumors. After absorbing highly tissue …

Photo-based nanomedicines using polymeric systems in the field of cancer imaging and therapy

P Husni, Y Shin, JC Kim, K Kang, ES Lee, YS Youn… - Biomedicines, 2020 - mdpi.com
The use of photo-based nanomedicine in imaging and therapy has grown rapidly. The
property of light in converting its energy into different forms has been exploited in the fields …