Chronic kidney disease (CKD) is a major and serious global health problem that leads to
kidney damage as well as multiple systemic diseases. Early diagnosis and treatment are two …

Diabetic nephropathy constitutes a devastating complication in patients with type 1 diabetes
mellitus, and its diagnosis is traditionally based on microalbuminuria. The aim of this review …

Diabetic kidney disease (DKD) occurs in 25%-40% of patients with diabetes. Given the dual
problems of a significant risk of progression from DKD to end-stage renal disease (ESRD) …

The pathophysiology of diabetic nephropathy (DN), one of the most serious complications in
diabetic patients and the leading cause of end-stage renal disease worldwide, is complex …

Abstract In 1927, Arthur C. Alport first published his description of a triad of symptoms in a
family with hereditary congenital haemorrhagic nephritis, deafness and ocular changes. A …

Diabetic nephropathy (DN), also named diabetic kidney disease (DKD), is a devastating
complication in patients with both type 1 and 2 diabetes mellitus (T1D and T2D) and its …

Diabetic nephropathy (DN) is a frequent and severe complication of diabetes mellitus (DM).
Its diagnosis in incipient stages may allow prompt interventions and an improved prognosis …

Background Podocyte specific proteins are dysregulated in diabetic nephropathy, though
the extent of their expression loss is not identical and may be subject to different regulatory …

Background Podocyte injury is an early feature of diabetic nephropathy (DN). Recently,
urinary exosomal Wilm's tumor-1 protein (WT1), shed by renal epithelial cells, has been …

Diabetic nephropathy (DN) is the most common cause of end-stage kidney disease in the
USA and accounts for a significant increase in morbidity and mortality in patients with …