Alzheimer's disease (AD) is a complex neurodegenerative disease in the elderly and the
most common cause of human dementia. AD is characterized by accumulation of abnormal …

Autophagy is an evolutionarily conserved catabolic cellular process that exerts antiviral
functions during a viral invasion. However, co-evolution and co-adaptation between viruses …

Positive-strand RNA viruses replicate in close association with rearranged intracellular
membranes. For hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus …

Autophagy has emerged as a critical lysosomal pathway that maintains cell function and
survival through the degradation of cellular components such as organelles and proteins …

All positive strand RNA viruses are known to replicate their genomes in close association
with intracellular membranes. In case of the hepatitis C virus (HCV), a member of the family …

Mechanistic target of rapamycin (mTOR, also known as mammalian target of rapamycin) is a
ubiquitous serine/threonine kinase that regulates cell growth, proliferation and survival …

Autophagy is a cellular response to starvation that generates autophagosomes to carry long-
lived proteins and cellular organelles to lysosomes for degradation. Activation of autophagy …

Macroautophagy is an important route in cellular maintenance, in the breakdown and reuse
of intracellular materials. It is closely related to endocytosis, the means by which the cell can …

Autophagy (macroautophagy) is a highly conserved intracellular and lysosome-dependent
degradation process in which autophagic substrates are enclosed and degraded by a …

Autophagy is an evolutionarily ancient process whereby eukaryotic cells eliminate
disposable or potentially dangerous cytoplasmic material, to support bioenergetic …