Objective: to identify and summarize studies examining both drug-drug interactions (DDI)
and adverse drug reactions (ADR) in older adults polymedicated. Methods: an integrative …

Pharmacological therapy in the elderly is particularly complicated and challenging. Due to
coexistence of three main predisposing factors (advanced age, multiple morbidity and …

Inappropriate prescribing is a risk factor for adverse drug reactions and hospitalizations in
the elderly and places a considerable burden on the healthcare system. Hence, it is …

Psychogeriatric primary care patients are frequently treated with excessive polypharmacy
(≥ 10 medications), leading to complications and increased costs. Such cases are rarely …

Background The population of developed countries is aging, leading to an increase in the
use of medication in daily practice, which can lead to serious treatment costs and irrational …

As the world's population ages, global health care systems will face the burden of chronic
diseases and polypharmacy use among older adults. The traditional tasks of medication …

Background: Drug therapy in the elderly needs an emphasis on age‐related changes in
drug pharmacokinetics and pharmacodynamics profile. Hospitalized elderly patients are at …

BACKGROUND: In polypharmacy patients, medication therapy management (MTM) services
provide a comprehensive review of current medications and future treatment goals …

Purpose Aging increases the prevalence of diseases. The elderly population is
consequently often exposed to complex medication regimens. Increased drug use is one of …

Abstract Background Direct oral anticoagulants (DOACs) have revolutionised anticoagulant
pharmacotherapy. However, DOAC-related medication incidents are known to be common …