The Chicken Pan-Genome Reveals Gene Content Variation and a Promoter Region Deletion in IGF2BP1 Affecting Body Size

K Wang, H Hu, Y Tian, J Li, A Scheben… - Molecular biology …, 2021 - academic.oup.com
Domestication and breeding have reshaped the genomic architecture of chicken, but the
retention and loss of genomic elements during these evolutionary processes remain …

An atlas of regulatory elements in chicken: A resource for chicken genetics and genomics

Z Pan, Y Wang, M Wang, Y Wang, X Zhu, S Gu… - Science …, 2023 - science.org
A comprehensive characterization of regulatory elements in the chicken genome across
tissues will have substantial impacts on both fundamental and applied research. Here, we …

Accelerated deciphering of the genetic architecture of agricultural economic traits in pigs using a low-coverage whole-genome sequencing strategy

R Yang, X Guo, D Zhu, C Tan, C Bian, J Ren… - …, 2021 - academic.oup.com
Background Uncovering the genetic architecture of economic traits in pigs is important for
agricultural breeding. However, high-density haplotype reference panels are unavailable in …

Research progress and applications of genome‐wide association study in farm animals

X Tan, Z He, AG Fahey, G Zhao, R Liu… - Animal Research and …, 2023 - Wiley Online Library
Exploring the genetic loci underlying economic traits is foundational for innovation in
modern animal breeding technology. Genome‐wide association studies (GWAS) have been …

Genomic prediction based on selective linkage disequilibrium pruning of low-coverage whole-genome sequence variants in a pure Duroc population

D Zhu, Y Zhao, R Zhang, H Wu, G Cai, Z Wu… - Genetics Selection …, 2023 - Springer
Background Although the accumulation of whole-genome sequencing (WGS) data has
accelerated the identification of mutations underlying complex traits, its impact on the …

Novel strategies to improve chicken performance and welfare by unveiling host-microbiota interactions through hologenomics

N Tous, S Marcos, F Goodarzi Boroojeni… - Frontiers in …, 2022 - frontiersin.org
Fast optimisation of farming practices is essential to meet environmental sustainability
challenges. Hologenomics, the joint study of the genomic features of animals and the …

[HTML][HTML] Chicken chromatin accessibility atlas accelerates epigenetic annotation of birds and gene fine-mapping associated with growth traits

XN Zhu, YZ Wang, C Li, HY Wu, R Zhang… - Zoological …, 2023 - ncbi.nlm.nih.gov
The development of epigenetic maps, such as the ENCODE project in humans, provides
resources for gene regulation studies and a reference for research of disease-related …

Identification of major loci and candidate genes for meat production-related traits in broilers

X Yang, J Sun, G Zhao, W Li, X Tan, M Zheng… - Frontiers in …, 2021 - frontiersin.org
Background Carcass traits are crucial characteristics of broilers. However, the underlying
genetic mechanisms are not well understood. In the current study, significant loci and major …

Serum metabolic profile and metabolome genome-wide association study in chicken

J Tian, X Zhu, H Wu, Y Wang, X Hu - Journal of Animal Science and …, 2023 - Springer
Background Chickens provide globally important livestock products. Understanding the
genetic and molecular mechanisms underpinning chicken economic traits is crucial for …

Genome‑wide association study and genomic prediction for growth traits in yellow-plumage chicken using genotyping-by-sequencing

R Yang, Z Xu, Q Wang, D Zhu, C Bian, J Ren… - Genetics Selection …, 2021 - Springer
Background Growth traits are of great importance for poultry breeding and production and
have been the topic of extensive investigation, with many quantitative trait loci (QTL) …