Alzheimer's disease (AD) is an aging-related neurological disorder characterized by
synaptic loss and dementia. Wnt/β-catenin signaling is an essential signal transduction …

Growing evidence suggests that synaptic signaling is compromised in the aging brain and in
Alzheimer's disease (AD), contributing to synaptic decline. Wnt signaling is a prominent …

Hormones regulate homeostasis by communicating through the bloodstream to the body's
organs, including the brain. As homeostatic regulators of brain function, some hormones …

Despite the improvements in life expectancy, neurodegenerative conditions have arguably
become the most dreaded maladies of older people. The neuroprotective and anti-ageing …

A proper balance between synapse assembly and disassembly is crucial for the formation of
functional neuronal circuits and synaptic plasticity in the adult brain. During development …

Neurodegenerative diseases (NDs) are conditions characterized by sensory, motor, and
cognitive impairments due to alterations in the structure and function of neurons in the …

The Wnt signalling system is essential for both the developing and adult central nervous
system. It regulates numerous cellular functions ranging from neurogenesis to blood brain …

Wnt/β-catenin (WβC) signaling pathway is an important signaling pathway for the
maintenance of cellular homeostasis from the embryonic developmental stages to …

Wnt signaling has emerged in recent years as a major player in both nervous system
development and adult synaptic plasticity. Of particular relevance to researchers studying …

This article is part of a Special Issue “Estradiol and Cognition”. Estradiol participates in the
regulation of the function and plasticity of synaptic circuits in key cognitive brain regions …