Surgery can cure or significantly improve both the frequency and the intensity of seizures in
patients with medication‐refractory epilepsy. The set of diagnostic and therapeutic …

Background Epilepsy is one of the most common neurological disorders. Approximately, one-
third of patients with epilepsy have seizures refractory to antiepileptic drugs and further …

Up to 30% of patients with epilepsy may not respond to antiepileptic drugs. Patients with
drug-resistant epilepsy (DRE) should undergo evaluation for seizure onset zone (SOZ) …

In recent years, artificial intelligence, particularly deep learning (DL), has demonstrated
utility in diverse areas of medicine. DL uses neural networks to automatically learn features …

Radiolabeled tracers allow visualization of not only perfusion, but receptors, function, and
metabolism as well. Although spatial resolution is lower than that of computed tomography …

Purpose Children with drug-resistant focal epilepsy have a compromised quality of life.
Epilepsy surgery can control or significantly reduce the seizures. We assessed and …

Background Cross-modality image estimation can be performed using generative
adversarial networks (GANs). To date, SPECT image estimation from another medical …

Brain perfusion single photon emission computed tomography (SPECT) scans were initially
developed in 1970's. A key radiopharmaceutical, hexamethylpropyleneamine oxime …

Please see the Editorial Comment by Patrick J. Peller discussing this article. Surgery is a
potentially curative treatment option for patients with medically refractory focal epilepsy …

Functional neuroimaging with positron emission tomography with 18 F-fluorodeoxyglucose
(18 F-FDG PET) and perfusion single photon emission computerized tomography (SPECT) …