[HTML][HTML] Western diet as a trigger of Alzheimer's disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration
A Więckowska-Gacek, A Mietelska-Porowska… - Ageing research …, 2021 - Elsevier
An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …
[HTML][HTML] AMPK signaling in diabetes mellitus, insulin resistance and diabetic complications: A pre-clinical and clinical investigation
M Entezari, D Hashemi, A Taheriazam… - Biomedicine & …, 2022 - Elsevier
Diabetes mellitus (DM) is considered as a main challenge in both developing and
developed countries, as lifestyle has changed and its management seems to be vital. Type I …
developed countries, as lifestyle has changed and its management seems to be vital. Type I …
Targeting microglial autophagic degradation in NLRP3 inflammasome-mediated neurodegenerative diseases
AG Wu, XG Zhou, G Qiao, LU Yu, Y Tang, LU Yan… - Ageing research …, 2021 - Elsevier
Neuroinflammation is considered as a detrimental factor in neurodegenerative diseases,
including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD) …
including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD) …
Activation of NLRP3 inflammasome and onset of Alzheimer's disease
H Bai, Q Zhang - Frontiers in immunology, 2021 - frontiersin.org
The nucleotide-binding domain leucine-rich repeat and pyrin domain containing receptor
protein 3 (NLRP3) is an important pattern recognition receptor in human innate immunity …
protein 3 (NLRP3) is an important pattern recognition receptor in human innate immunity …
Lychee (Litchi chinensis Sonn.) Pulp Phenolics Activate the Short-Chain Fatty Acid-Free Fatty Acid Receptor Anti-inflammatory Pathway by Regulating Microbiota and …
G Huang, Z Wang, G Wu, R Zhang… - Journal of Agricultural …, 2021 - ACS Publications
The preventive effect of lychee pulp phenolics (LPP) on dextran sulfate sodium (DSS)-
induced colitis of mice and its underlying mechanisms were investigated in this research …
induced colitis of mice and its underlying mechanisms were investigated in this research …
Role of α-synuclein in microglia: Autophagy and phagocytosis balance neuroinflammation in Parkinson's disease
QK Lv, KX Tao, XB Wang, XY Yao, MZ Pang… - Inflammation …, 2023 - Springer
Background Parkinson's disease (PD) is the second most common neurodegenerative
disease, and is characterized by accumulation of α-synuclein (α-syn). Neuroinflammation …
disease, and is characterized by accumulation of α-synuclein (α-syn). Neuroinflammation …
The role of NLRP3 inflammasome in Alzheimer's disease and potential therapeutic targets
T Liang, Y Zhang, S Wu, Q Chen, L Wang - Frontiers in Pharmacology, 2022 - frontiersin.org
Alzheimer's disease (AD) is a common age-related neurodegenerative disease
characterized by progressive cognitive dysfunction and behavioral impairment. The typical …
characterized by progressive cognitive dysfunction and behavioral impairment. The typical …
Dietary plant polyphenols as the potential drugs in neurodegenerative diseases: current evidence, advances, and opportunities
L Yan, MS Guo, Y Zhang, L Yu, JM Wu… - Oxidative Medicine …, 2022 - Wiley Online Library
Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD),
and Huntington's disease (HD), are characterized by the progressive degeneration of …
and Huntington's disease (HD), are characterized by the progressive degeneration of …
Role of NLRP3 inflammasome and its inhibitors as emerging therapeutic drug candidate for Alzheimer's disease: a review of mechanism of activation, regulation, and …
B Sharma, G Satija, A Madan, M Garg, MM Alam… - Inflammation, 2023 - Springer
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders. The
etiology and pathology of AD are complicated, variable, and yet to be completely …
etiology and pathology of AD are complicated, variable, and yet to be completely …
Polygala saponins inhibit NLRP3 inflammasome-mediated neuroinflammation via SHP-2-Mediated mitophagy
WQ Qiu, W Ai, FD Zhu, Y Zhang, MS Guo… - Free Radical Biology …, 2022 - Elsevier
Activation of the NLRP3 inflammasome and its mediated neuroinflammation are implicated
in neurodegenerative diseases, while mitophagy negatively regulates NLRP3 …
in neurodegenerative diseases, while mitophagy negatively regulates NLRP3 …