RNA-dependent RNA polymerase as a target for COVID-19 drug discovery

W Zhu, CZ Chen, K Gorshkov, M Xu… - … the Science of Drug …, 2020 - journals.sagepub.com
COVID-19 respiratory disease caused by the severe acute respiratory syndrome coronavirus-
2 (SARS-CoV-2) has rapidly become a global health issue since it emerged in December …

Remdesivir in the treatment of coronavirus disease 2019 (COVID-19): a simplified summary

MA Hendaus - Journal of Biomolecular Structure and Dynamics, 2021 - Taylor & Francis
The pandemic of COVID-19 (Coronavirus Disease-2019) is an extremely contagious
respiratory illness due to a novel coronavirus, SARS-CoV-2. Certain drugs have several …

An investigation into the identification of potential inhibitors of SARS-CoV-2 main protease using molecular docking study

S Das, S Sarmah, S Lyndem… - Journal of Biomolecular …, 2021 - Taylor & Francis
A new strain of a novel infectious disease affecting millions of people, caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has recently been declared as a …

Using X-ray images and deep learning for automated detection of coronavirus disease

K El Asnaoui, Y Chawki - Journal of Biomolecular Structure and …, 2021 - Taylor & Francis
Coronavirus is still the leading cause of death worldwide. There are a set number of COVID-
19 test units accessible in emergency clinics because of the expanding cases daily …

SARS-CoV-2 RNA dependent RNA polymerase (RdRp) targeting: an in silico perspective

AA Elfiky - Journal of Biomolecular Structure and Dynamics, 2021 - Taylor & Francis
New treatment against SARS-CoV-2 now is a must. Nowadays, the world encounters a huge
health crisis by the COVID-19 viral infection. Nucleotide inhibitors gave a lot of promising …

A molecular modeling approach to identify effective antiviral phytochemicals against the main protease of SARS-CoV-2

R Islam, MR Parves, AS Paul, N Uddin… - Journal of …, 2021 - Taylor & Francis
The main protease of SARS-CoV-2 is one of the important targets to design and develop
antiviral drugs. In this study, we have selected 40 antiviral phytochemicals to find out the …

Targeting SARS-CoV-2 spike protein of COVID-19 with naturally occurring phytochemicals: an in silico study for drug development

P Pandey, JS Rane, A Chatterjee, A Kumar… - Journal of …, 2021 - Taylor & Francis
Spike glycoprotein, a class I fusion protein harboring the surface of SARS-CoV-2 (SARS-
CoV-2S), plays a seminal role in the viral infection starting from recognition of the host cell …

Stilbene-based natural compounds as promising drug candidates against COVID-19

HM Wahedi, S Ahmad, SW Abbasi - Journal of Biomolecular …, 2021 - Taylor & Francis
The pandemic coronavirus disease (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) presents a great threat to public health. Currently …

Potential inhibitors of coronavirus 3-chymotrypsin-like protease (3CLpro): an in silico screening of alkaloids and terpenoids from African medicinal plants

GA Gyebi, OB Ogunro, AP Adegunloye… - Journal of …, 2021 - Taylor & Francis
The novel coronavirus disease 2019 (COVID-19) caused by SARS-COV-2 has raised
myriad of global concerns. There is currently no FDA approved antiviral strategy to alleviate …

Identification of phytochemical inhibitors against main protease of COVID-19 using molecular modeling approaches

A Kumar, G Choudhir, SK Shukla… - Journal of …, 2021 - Taylor & Francis
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel corona virus that
causes corona virus disease 2019 (COVID-19). The COVID-19 rapidly spread across the …