Protein glycosylation in cancer

SR Stowell, T Ju, RD Cummings - Annual Review of Pathology …, 2015 - annualreviews.org
Neoplastic transformation results in a wide variety of cellular alterations that impact the
growth, survival, and general behavior of affected tissue. Although genetic alterations …

[HTML][HTML] Guide for diagnosis and treatment of hepatocellular carcinoma

MH Attwa, SA El-Etreby - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is ranked as the 5 th common type of cancer worldwide
and is considered as the 3 rd common reason for cancer-related deaths. HCC often occurs …

Human body fluid proteome analysis

S Hu, JA Loo, DT Wong - Proteomics, 2006 - Wiley Online Library
The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …

Glycosylation‐based serum biomarkers for cancer diagnostics and prognostics

A Kirwan, M Utratna, ME O'Dwyer… - BioMed research …, 2015 - Wiley Online Library
Cancer is the second most common cause of death in developed countries with
approximately 14 million newly diagnosed individuals and over 6 million cancer‐related …

Diagnosing and monitoring hepatocellular carcinoma with alpha-fetoprotein: new aspects and applications

EN Debruyne, JR Delanghe - Clinica chimica acta, 2008 - Elsevier
Hepatocellular carcinoma is the 5th most common cancer in the world. Prognosis for this
disease is poor since hepatocellular carcinoma is mostly diagnosed at an advanced stage …

[HTML][HTML] Short O-GalNAc glycans: regulation and role in tumor development and clinical perspectives

J Chia, G Goh, F Bard - Biochimica Et Biophysica Acta (BBA)-General …, 2016 - Elsevier
Background While the underlying causes of cancer are genetic modifications, changes in
cellular states mediate cancer development. Tumor cells display markedly changed …

A glycoform‐resolved dual‐modal ratiometric immunoassay improves the diagnostic precision for hepatocellular carcinoma

P Li, J Pang, S Xu, H He, Y Ma… - Angewandte Chemie …, 2022 - Wiley Online Library
The glycosylation pattern of alpha fetoprotein (AFP) paves the basis for precise early
diagnosis of hepatocellular carcinoma (HCC). However, existing analytical methods ignore …

Lectin capture strategies combined with mass spectrometry for the discovery of serum glycoprotein biomarkers

RR Drake, EE Schwegler, G Malik, J Diaz… - Molecular & Cellular …, 2006 - ASBMB
The application of mass spectrometry to identify disease biomarkers in clinical fluids like
serum using high throughput protein expression profiling continues to evolve as technology …

Serological markers of liver cancer

MF Yuen, CL Lai - Best Practice & Research Clinical Gastroenterology, 2005 - Elsevier
Serological markers for hepatocellular carcinoma (HCC) are important for early diagnosis,
as well as monitoring of tumour aggressiveness, treatment responsiveness, recurrence and …

Biology of hepatocellular carcinoma

RWC Pang, JW Joh, PJ Johnson, M Monden… - Annals of surgical …, 2008 - Springer
Hepatocellular carcinoma (HCC) is a common cancer in the world due to high prevalence of
hepatitis B or C virus infection. Research in recent years has uncovered important molecular …