Chirality plays a crucial role in life-sustaining processes, and for this reason asymmetric
synthesis has been a central research theme in many research groups in the field of organic …

The past two decades have witnessed unprecedented development and advancement of
chiral phosphoric acid catalysis. Therefore, it is not surprising that the attempts to synthesize …

A general and efficient method for accessing enantiomerically pure arylpyrroles by utilizing
the catalytic asymmetric Paal-Knorr reaction has been developed for the first time. A wide …

Nonbiaryl NC atropisomer is an important structural scaffold, which is present in natural
products, medicines and chiral ligands. However the direct enantioselective CH amination to …

An atropisomer is a member of a subclass of restricted rotational conformers–this restricted
rotation giving rise to stereogenic sigma bonds–that can be isolated as separate chemical …

Pentatomic heterobiaryl performs as a key structural motif in various natural products and
bioactive compounds. With the rapid growth of asymmetric catalysis, five‐membered …

For the first time, a desymmetrization strategy empowered the assembly of a class of
optically pure spirooxindole–urazoles possessing an N-Ar stereogenic axis via remote …

An unprecedented AgI‐catalyzed efficient method for the coupling of imino ethers and enol
diazoacetates through a [3+ 2]‐cycloaddition/C− O bond cleavage/[1, 5]‐proton transfer …

A readily prepared C2-symmetric, α-hydrogen-substituted chiral hydroxylamine serves as a
precatalyst to generate a chiral nitroxide in situ. This chiral nitroxide catalyst in combination …

An atroposelective coupling of indoles with chiral amino acid-based sulfonamides mediated
by hypohalides is described. A series of 2-amido-3-haloindoles with a C–N chiral axis are …