Cefiderocol, a siderophore cephalosporin, as a treatment option for infections caused by carbapenem-resistant Enterobacterales

KS Kaye, T Naas, JM Pogue, GM Rossolini - Infectious Diseases and …, 2023 - Springer
Carbapenem-resistant Enterobacterales (CRE) remain a significant public health threat,
and, despite recent approvals, new antibiotics are needed. Severe infections caused by …

Evaluation of inhaled nitric oxide (iNO) treatment for moderate-to-severe ARDS in critically ill patients with COVID-19: a multicenter cohort study

K Al Sulaiman, GB Korayem, AF Altebainawi… - Critical Care, 2022 - Springer
Background Inhaled nitric oxide (iNO) is used as rescue therapy in patients with refractory
hypoxemia due to severe COVID-19 acute respiratory distress syndrome (ARDS) despite the …

Carbapenems versus β-lactam and β-lactamase inhibitors for treatment of nosocomial pneumonia: A systematic review and meta-analysis

HQ Cang, XH Quan, XH Chu, Y Liang, X Yang, J Li - Heliyon, 2023 - cell.com
Background Carbapenems and β-lactam and β‐lactamase inhibitors (BLBLIs) have been
used empirically in nosocomial pneumonia, but their efficacy and safety are controversial …

Antecedents of risky financial investment intention among higher education students: a mediating moderating model using structural equation modeling

IA Elshaer, AEE Sobaih - Mathematics, 2023 - mdpi.com
The current study examines the direct effect of investment awareness and university
education support on students' risky financial investment intentions. Additionally, it examines …

Prevalence of multidrug-resistant pathogens causing neonatal early and late onset sepsis, a retrospective study from the tertiary referral children's hospital

P Fang, K Gao, J Yang, T Li, W Gong… - Infection and Drug …, 2023 - Taylor & Francis
Introduction Sepsis is the most severe infectious disease with the highest mortality rate,
particularly among neonates admitted to the neonatal intensive care unit (NICU). This study …

Molecular characterization of carbapenem-resistance in Gram-negative isolates obtained from clinical samples at Jimma Medical Center, Ethiopia

M Gashaw, EK Gudina, S Ali, L Gabriele… - Frontiers in …, 2024 - frontiersin.org
Background In resource-constrained settings, limited antibiotic options make treating
carbapenem-resistant bacterial infections difficult for healthcare providers. This study aimed …

Genetic predictive factors for nonsusceptible phenotypes and multidrug resistance in expanded-spectrum cephalosporin-resistant uropathogenic Escherichia coli from …

N Jackson, CR Belmont, NJ Tarlton, YH Allegretti… - MSphere, 2022 - Am Soc Microbiol
Antimicrobial resistance in urinary tract infections (UTIs) is a major public health concern.
This study aims to characterize the phenotypic and genetic basis of multidrug resistance …

The role of inhaled corticosteroids (ICS) in critically Ill patients with COVID-19: A multicenter, cohort study

K Al Sulaiman, O Aljuhani, K Al Aamer… - Journal of Intensive …, 2022 - journals.sagepub.com
Background: Severe coronavirus disease 2019 (COVID-19) can boost the systematic
inflammatory response in critically ill patients, causing a systemic hyperinflammatory state …

An analysis of differences in Carbapenem-resistant Enterobacterales in different regions: a multicenter cross-sectional study

B Guo, P Li, B Qin, S Wang, W Zhang, Y Shi… - BMC Infectious …, 2024 - Springer
Objective This study aimed to explore the characteristics of carbapenem-resistant
Enterobacterales (CRE) patients in the intensive care unit (ICU) in different regions of Henan …

Association between tocilizumab and emerging multidrug-resistant organisms in critically ill patients with COVID-19: A multicenter, retrospective cohort study

O Aljuhani, K Al Sulaiman, A Alshabasy, K Eljaaly… - BMC Infectious …, 2021 - Springer
Abstract Background Tocilizumab is an IgG1 class recombinant humanized monoclonal
antibody that directly inhibits the IL-6 receptor. Several randomized clinical trials have …