Cochlear implant research and development in the twenty-first century: a critical update

RP Carlyon, T Goehring - Journal of the Association for Research in …, 2021 - Springer
Cochlear implants (CIs) are the world's most successful sensory prosthesis and have been
the subject of intense research and development in recent decades. We critically review the …

Safety of long-term electrical peripheral nerve stimulation: review of the state of the art

C Günter, J Delbeke, M Ortiz-Catalan - Journal of neuroengineering and …, 2019 - Springer
Background Electrical stimulation of peripheral nerves is used in a variety of applications
such as restoring motor function in paralyzed limbs, and more recently, as means to provide …

Auditory-nerve responses to varied inter-phase gap and phase duration of the electric pulse stimulus as predictors for neuronal degeneration

D Ramekers, H Versnel, SB Strahl, EM Smeets… - Journal of the …, 2014 - Springer
After severe hair cell loss, secondary degeneration of spiral ganglion cells (SGCs) is
observed—a gradual process that spans years in humans but only takes weeks in guinea …

Assessing the electrode-neuron interface with the electrically evoked compound action potential, electrode position, and behavioral thresholds

L DeVries, R Scheperle, JA Bierer - … of the Association for Research in …, 2016 - Springer
Variability in speech perception scores among cochlear implant listeners may largely reflect
the variable efficacy of implant electrodes to convey stimulus information to the auditory …

The electrically evoked compound action potential: from laboratory to clinic

S He, HFB Teagle, CA Buchman - Frontiers in neuroscience, 2017 - frontiersin.org
The electrically evoked compound action potential (eCAP) represents the synchronous firing
of a population of electrically stimulated auditory nerve fibers. It can be directly recorded on …

Importance of cochlear health for implant function

BE Pfingst, N Zhou, DJ Colesa, MM Watts, SB Strahl… - Hearing research, 2015 - Elsevier
Amazing progress has been made in providing useful hearing to hearing-impaired
individuals using cochlear implants, but challenges remain. One such challenge is …

Effect of interphase gap and pulse duration on electrically evoked potentials is correlated with auditory nerve survival

P Prado-Guitierrez, LM Fewster, JM Heasman… - Hearing research, 2006 - Elsevier
We investigated the effect of pulse duration (PD) and interphase-gap (IPG) on the electrically-
evoked auditory brain stem response (EABR) and viiith nerve compound action potential …

Probing the electrode-neuron interface with focused cochlear implant stimulation

J Arenberg Bierer - Trends in amplification, 2010 - journals.sagepub.com
Cochlear implants are highly successful neural prostheses for persons with severe or
profound hearing loss who gain little benefit from hearing aid amplification. Although …

Cochlear health and cochlear-implant function

KC Schvartz-Leyzac, DJ Colesa, DL Swiderski… - Journal of the …, 2023 - Springer
The cochlear implant (CI) is widely considered to be one of the most innovative and
successful neuroprosthetic treatments developed to date. Although outcomes vary, CIs are …

Neurotrophins and their role in the cochlea

D Ramekers, H Versnel, W Grolman, SFL Klis - Hearing research, 2012 - Elsevier
Spiral ganglion cell (SGC) degeneration following hair cell loss can be prevented by
administration of exogenous neurotrophic factors. Many of these neurotrophic factors, in …