Efficient computation and statistical assessment of transfer entropy

P Boba, D Bollmann, D Schoepe, N Wester… - Frontiers in …, 2015 - frontiersin.org
The analysis of complex systems frequently poses the challenge to distinguish correlation
from causation. Statistical physics has inspired very promising approaches to search for …

Three-body interactions improve contact prediction within direct-coupling analysis

M Schmidt, K Hamacher - Physical review E, 2017 - APS
The prediction of residue contacts in a protein solely from sequence information is a
promising approach to computational structure prediction. Recent developments use …

hoDCA: higher order direct-coupling analysis

M Schmidt, K Hamacher - BMC bioinformatics, 2018 - Springer
Background Direct-coupling analysis (DCA) is a method for protein contact prediction from
sequence information alone. Its underlying principle is parameter estimation for a …

Visual analysis of patterns in multiple amino acid mutation graphs

O Lenz, F Keul, S Bremm, K Hamacher… - … IEEE Conference on …, 2014 - ieeexplore.ieee.org
Proteins are essential parts in all living organisms. They consist of sequences of amino
acids. An interaction with reactive agent can stimulate a mutation at a specific position in the …

Consistent Quantification of Complex Dynamics via a Novel Statistical Complexity Measure

F Keul, K Hamacher - Entropy, 2022 - mdpi.com
Natural systems often show complex dynamics. The quantification of such complex
dynamics is an important step in, eg, characterization and classification of different systems …

[PDF][PDF] Statistische Modelle und Inferenz der strukturellen Biophysik

M Schmidt - 2022 - d-nb.info
Zusammenfassung Mathematische Modelle sind essentielle Werkzeuge für die
Strukturanalyse von Biomolekülen und ergänzen Experimente. Dank enorm steigender …

[PDF][PDF] Using Lisp Macro-Facilities for Transferable Statistical Tests.

K Hamacher - ELS, 2016 - kay-hamacher.de
Model-free statistical tests are purely data-driven approaches to assess correlations and
other interdependencies between observable quantities. The few, distinct patterns how to …

Graphenrekonstruktion anhand abhängiger Zeitreihen in biologischen Netzwerken

P Boba - 2019 - tuprints.ulb.tu-darmstadt.de
Die Biologie befasst sich mit dem Aufbau und der Organisation von Lebewesen. Bei beiden
Aspekten finden sich auf verschiedenen Abstraktionsebenen Phänomene, die sich als …

[引用][C] Emerging computational methods for the life sciences workshop 2012

J Qiu, I Foster, C Goble - Concurrency and Computation …, 2014 - Wiley Online Library
1 BACKGROUND Computing systems are rapidly changing with multicore, graphics
processing units (GPUs), clusters, volunteer systems, clouds, and grids offering a confusing …