Advancing Raman microspectroscopy for cellular and subcellular analysis: towards in vitro high-content spectralomic analysis

HJ Byrne, F Bonnier, A Casey, M Maher, J McIntyre… - Applied Optics, 2018 - opg.optica.org
In the confocal mode, Raman microspectroscopy can profile the biochemical content of
biological cells at a subcellular level, and any changes to it by exogenous agents, such as …

Potential use of pentoxifylline in cancer therapy

G Golunski, A Woziwodzka… - Current pharmaceutical …, 2018 - ingentaconnect.com
Background: Pentoxifylline (PTX) is a drug commonly used in the treatment of intermittent
claudication. However, numerous research groups report that PTX also may potentially be …

C60 fullerene enhances cisplatin anticancer activity and overcomes tumor cell drug resistance

S Prylutska, R Panchuk, G Gołuński, L Skivka… - Nano Research, 2017 - Springer
We formulated and analyzed a novel nanoformulation of the anticancer drug cisplatin (Cis)
with C 60 fullerene (C 60+ Cis complex) and showed its higher toxicity toward tumor cell …

Pentoxifylline and thiamine ameliorate rhabdomyolysis-induced acute kidney injury in rats via suppressing TLR4/NF-κB and NLRP-3/caspase-1/gasdermin mediated …

L Al-Kharashi, H Attia, A Alsaffi, T Almasri… - Toxicology and Applied …, 2023 - Elsevier
Acute kidney injury (AKI) is a common complication of rhabdomyolysis (RM), a syndrome
characterized by skeletal muscle damage resulting in renal tubular oxidative stress …

Monitoring doxorubicin cellular uptake and trafficking using in vitro Raman microspectroscopy: short and long time exposure effects on lung cancer cell lines

Z Farhane, F Bonnier, HJ Byrne - Analytical and bioanalytical chemistry, 2017 - Springer
Raman microspectroscopy is a non-invasive, in vitro analytical tool which is being
increasingly explored for its potential in clinical applications and monitoring the uptake …

Thermoresponsive supramolecular micellar drug delivery system based on star-linear pseudo-block polymer consisting of β-cyclodextrin-poly (N-isopropylacrylamide) …

X Song, J Zhu, Y Wen, F Zhao, ZX Zhang, J Li - Journal of colloid and …, 2017 - Elsevier
Chemotherapy is facing several limitations such as low water solubility of anticancer drugs
and multidrug resistance (MDR) in cancer cells. To overcome these limitations, a …

Fluorescent alloyed CdZnSeS/ZnS nanosensor for doxorubicin detection

SA Mescheryakova, IS Matlakhov, PD Strokin… - Biosensors, 2023 - mdpi.com
Doxorubicin (DOX) is widely used in chemotherapy as an anti-tumor drug. However, DOX is
highly cardio-, neuro-and cytotoxic. For this reason, the continuous monitoring of DOX …

Doxorubicin kinetics and effects on lung cancer cell lines using in vitro Raman micro‐spectroscopy: binding signatures, drug resistance and DNA repair

Z Farhane, F Bonnier, O Howe, A Casey… - Journal of …, 2018 - Wiley Online Library
Raman micro‐spectroscopy is a non‐invasive analytical tool, whose potential in cellular
analysis and monitoring drug mechanisms of action has already been demonstrated, and …

Pentoxifylline changes the balance of immune cell population in breast tumor-infiltrating lymphocytes

MH Kazemi, M Shokrollahi Barough… - Medical Oncology, 2023 - Springer
Immunotherapy utilizing tumor-infiltrating lymphocytes (TILs) is a promising approach for
cancer treatment. Pentoxifylline (PTXF), a xanthine derivative, exhibits antitumor properties …

Antimicrobial, Cytotoxic and Mutagenic Activity of Gemini QAS Derivatives of 1,4:3,6-Dianhydro-l-iditol

K Sikora, A Nowacki, P Szweda, A Woziwodzka… - Molecules, 2022 - mdpi.com
A series of quaternary diammonium salts derivatives of 1, 4: 3, 6-dianhydro-l-iditol were
synthesized, using isommanide (1, 4: 3, 6-dianhydro-d-mannitol) as a starting material. Both …