[HTML][HTML] Potential pitfalls of using fractional anisotropy, axial diffusivity, and radial diffusivity as biomarkers of cerebral white matter microstructure

CR Figley, MN Uddin, K Wong, J Kornelsen… - Frontiers in …, 2022 - frontiersin.org
Fractional anisotropy (FA), axial diffusivity (AD), and radial diffusivity (RD) are commonly
used as MRI biomarkers of white matter microstructure in diffusion MRI studies of …

Magnetization transfer contrast and chemical exchange saturation transfer MRI. Features and analysis of the field-dependent saturation spectrum

PCM Van Zijl, WW Lam, J Xu, L Knutsson, GJ Stanisz - Neuroimage, 2018 - Elsevier
Abstract Magnetization Transfer Contrast (MTC) and Chemical Exchange Saturation
Transfer (CEST) experiments measure the transfer of magnetization from molecular protons …

[HTML][HTML] Modelling and interpretation of magnetization transfer imaging in the brain

JG Sled - Neuroimage, 2018 - Elsevier
Magnetization transfer contrast has yielded insight into brain tissue microstructure changes
across the lifespan and in a range of disorders. This progress has been aided by the …

The relayed nuclear Overhauser effect in magnetization transfer and chemical exchange saturation transfer MRI

Y Zhou, C Bie, PCM van Zijl, NN Yadav - NMR in biomedicine, 2023 - Wiley Online Library
Magnetic resonance (MR) is a powerful technique for noninvasively probing molecular
species in vivo but suffers from low signal sensitivity. Saturation transfer (ST) MRI …

Quantitative myelin imaging with MRI and PET: an overview of techniques and their validation status

CWJ van der Weijden, E Biondetti, IW Gutmann… - Brain, 2023 - academic.oup.com
Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …

Validating the sensitivity of inhomogeneous magnetization transfer (ihMT) MRI to myelin with fluorescence microscopy

G Duhamel, VH Prevost, M Cayre, A Hertanu… - Neuroimage, 2019 - Elsevier
Abstract Inhomogeneous Magnetization Transfer (ihMT) is a development from the MT MRI
technique. IhMT can be considered as a dipolar order relaxation time (T 1D) weighted …

A multiparametric analysis of white matter maturation during late childhood and adolescence

BL Geeraert, RM Lebel, C Lebel - Human brain mapping, 2019 - Wiley Online Library
White matter development has been well described using diffusion tensor imaging (DTI), but
the microstructural processes driving development remain unclear due to methodological …

A comparison of inhomogeneous magnetization transfer, myelin volume fraction, and diffusion tensor imaging measures in healthy children

BL Geeraert, RM Lebel, AC Mah, SC Deoni, DC Alsop… - Neuroimage, 2018 - Elsevier
Sensitive and specific biomarkers of myelin can help define baseline brain health and
development, identify and monitor disease pathology, and evaluate response to treatment …

Whole brain inhomogeneous magnetization transfer (ihMT) imaging: sensitivity enhancement within a steady‐state gradient echo sequence

S Mchinda, G Varma, VH Prevost… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose To implement, characterize, and optimize an interleaved inhomogeneous
magnetization transfer (ihMT) gradient echo sequence allowing for whole‐brain imaging …

The physical mechanism of “inhomogeneous” magnetization transfer MRI

AP Manning, KL Chang, AL MacKay… - Journal of Magnetic …, 2017 - Elsevier
Inhomogeneous MT (ihMT) is a new magnetic resonance imaging technique that shows
promise for myelin selectivity. Materials with a high proportion of lipids, such as white matter …