Enzymes are an attractive alternative in the asymmetric syntheses of chiral building blocks.
To meet the requirements of industrial biotechnology and to introduce new functionalities …

Progress in technology and algorithms throughout the past decade has transformed the field
of protein design and engineering. Computational approaches have become well-engrained …

Pollution, accidents, and misinformation have earned the pharmaceutical and chemical
industry a poor public reputation, despite their undisputable importance to society …

Cyclohexanone monooxygenase (CHMO) is a promising biocatalyst for industrial reactions
owing to its broad substrate spectrum and excellent regio‐, chemo‐, and enantioselectivity …

Baeyer–Villiger monooxygenases (BVMOs) are useful enzymes for organic synthesis as
they enable the direct and highly regio-and stereoselective oxidation of ketones to esters or …

Biocatalytic site-selective (regioselective) organic transformations have been practiced for
decades, but the traditional limitations of enzymes regarding narrow substrate acceptance …

Abstract Baeyer-Villiger monooxygenases (BVMOs) are versatile biocatalysts for the
conversion of ketones to lactones or esters while also being able to efficiently oxidize …

The Baeyer–Villiger monooxygenases (BVMOs) are a family of bacterial flavoproteins that
catalyze the synthetically useful Baeyer–Villiger oxidation reaction. This involves the …

The combinatorial space of an enzyme sequence has astronomical possibilities and
exploring it with contemporary experimental techniques is arduous and often ineffective …

To expand the available set of Baeyer–Villiger monooxygenases (BVMOs), we have created
expression constructs for producing 22 Type I BVMOs that are present in the genome of …