Amorphous solid dispersions (ASDs) are a proven system for achieving a supersaturated
state of drug, in which the concentration of drug is greater than its crystalline solubility. The …

Selective laser sintering (SLS) 3D printing is capable of revolutionising pharmaceutical
manufacturing, by producing amorphous solid dispersions in a one-step manufacturing …

In this study, a solidified self-nanoemulsifying drug delivery system (solidified SNEDDS) and
surface-modified microspheres were developed for enhancing the oral bioavailability of …

The impact of drug loading on the compaction properties of itraconazole (ITZ)-poly
(vinylpyrrolidone-co-vinyl-acetate)(PVPVA) amorphous solid dispersions (ASDs) was …

Lutein has been used as a dietary supplement for the treatment of eye diseases, especially
age-related macular degeneration. For oral formulations, we investigated lutein stability in …

Solubility of the drug is an important property of the drug as it affects the release, absorption,
dissolution rate and ultimately bioavailability of the drug. Hence, the poorly aqueous soluble …

Due to poor solubility and stability in acid conditions, the gastrointestinal administration of
stiripentol (STP) is still a significant challenge. This study aimed to explore the applicability …

In the present study, in order to improve the solubility and bioavailability of poorly water-
soluble dexibuprofen, a novel dexibuprofen-loaded solid dispersion was developed using …

Mesupron, the first-in-class inhibitor of urokinase-type plasminogen activator (uPA) is known
to regulate cell proliferation and migration, and is under investigation for the treatment of …

We present the anti-solvent precipitation of hydrophobic drugs griseofulvin (GF) and
sulfamethoxazole (SMZ) in the presence of carboxylated carbon nanotubes (f-CNTs). The …