The human collectin, mannose‐binding lectin (MBL), is an important protein of the humoral
innate immune system. With multiple carbohydrate‐recognition domains, it is able to bind to …

Mannan‐binding lectin (MBL) is a plasma collectin (C‐type lectin with a collagen‐like
domain) and is considered an important component of innate immunity. Circulating MBL is …

Otitis media (OM) is a middle ear infection associated with inflammation and pain. This
disease frequently afflicts humans and is the major cause of hearing loss worldwide. OM …

Background Mannose-binding lectin (MBL) and MBL-associated serine proteases 2 (MASP-
2) are important proteins in the lectin pathway of the immune system. Polymorphism of MBL …

Mannan-binding lectin (MBL) is an innate pattern recognition molecule known to play a key
role in pathogen clearance. As MBL2 gene polymorphism is associated to an increased …

Background L-ficolin (encoded by FCN2) binds to acetylated sugar moieties of many
pathogens, including Trypanosoma cruzi, promoting their phagocytosis and lysis by the …

The mannose binding lectin (MBL2) polymorphism is responsible for a common
immunodeficiency in the human species. There were suggestions that the MBL2 …

Mannose-binding lectin (MBL) initiates complement on Trypanosoma cruzi through the MBL-
associated serine protease 2 (MASP2). We haplotyped six MASP2 polymorphisms in 208 …

Hepatitis C virus (HCV) is a major cause of hepatic disease and of liver transplantation
worldwide. Mannan-binding lectin (MBL), encoded by the MBL2 gene, can have an …

Abstract Mannose-binding lectin (MBL2) variants that decrease the plasma level of the
protein or encode dysfunctional proteins are frequently associated with the severity of a …