The differences between males and females begin shortly after birth, continue throughout
prenatal development, and eventually extend into childhood and adult life. Male embryos …

In recent decades, both clinical and animal studies have shown that fetal growth restriction
(FGR), caused by exposure to adverse uterine environments, is a risk factor for hypertension …

Background Telomere length is an important indicator of tumor progression and survival for
cancer patients. Previous work investigated the associations between genetically predicted …

The relationship between birth weight and osteoporosis was inconsistent in previous
observational studies. Therefore, we performed a systematic evaluation to determine the …

Background The evidence from observational studies on the association between the use of
aspirin and the risk of hayfever or allergic rhinitis is conflicting, with a dearth of high-quality …

Background Epidemiological studies demonstrated that adverse in utero environment was
associated with increased risk of offspring high blood pressure, by using birthweight as the …

Context Observational studies have shown associations of birth weight (BW) with coronary
heart disease (CHD), but results are inconsistent and do not distinguish the fetal or maternal …

Genome-wide association studies (GWASs) have successfully identified a large amount of
single-nucleotide polymorphisms associated with many complex phenotypes in diverse …

Objectives: A large meta-analysis indicated a more pronounced association between lower
birth weight (BW) and diseases in women but less concern about the causality between BW …

Cardiovascular diseases (CVDs) remain the main cause of morbidity and mortality
worldwide. The pathological mechanism and underlying biological processes of these …