The SLC38A5/SNAT5 amino acid transporter: from pathophysiology to pro-cancer roles in the tumor microenvironment

G Taurino, M Chiu, MG Bianchi… - American Journal of …, 2023 - journals.physiology.org
SLC38A5/SNAT5 is a system N transporter that can mediate net inward or outward
transmembrane fluxes of neutral amino acids coupled with Na+ (symport) and H+ (antiport) …

Plasma-Like Culture Medium for the Study of Viruses

MV Golikov, B Bartosch, OA Smirnova, ON Ivanova… - Mbio, 2023 - Am Soc Microbiol
Viral infections attract more and more attention, especially after the emergence of novel
zoonotic coronaviruses and the monkeypox virus over the last 2 decades. Research on …

Evaluation of the impact of customized serum-free culture medium on the production of clinical-grade human umbilical cord mesenchymal stem cells: insights for future …

L Zhao, B Ni, J Li, R Liu, Q Zhang, Z Zheng… - Stem Cell Research & …, 2024 - Springer
Background The selection of suitable culture medium is critical for achieving good clinical
outcomes in cell therapy. To support the commercial application of stem cell therapy …

Asparagine transport through SLC1A5/ASCT2 and SLC38A5/SNAT5 is essential for BCP‐ALL cell survival and a potential therapeutic target

G Taurino, E Dander, M Chiu, G Pozzi… - British Journal of …, 2024 - Wiley Online Library
B‐cell precursor acute lymphoblastic leukaemia (BCP‐ALL) blasts strictly depend on the
transport of extra‐cellular asparagine (Asn), yielding a rationale for L‐asparaginase …

The effects of culture conditions on cell metabolism and function

J Tan - 2024 - repository.cam.ac.uk
The in vitro microenvironment profoundly affects the capacity of cell culture to model
physiological and pathophysiological states. Central to the modern optimisation of cell …

Physiologically relevant culture medium Plasmax improves human placental trophoblast stem cell function

G Avellino, R Deshmukh, SN Rogers… - … of Physiology-Cell …, 2023 - journals.physiology.org
Human trophoblast cultures provide powerful tools to model key processes of placental
development. In vitro trophoblast studies to date have relied on commercial media that …