Micronuclei (MN) are extra-nuclear bodies that contain damaged chromosome fragments
and/or whole chromosomes that were not incorporated into the nucleus after cell division …

Arsenic is a human carcinogen with weak mutagenic properties that induces tumors through
mechanisms not yet completely understood. People worldwide are exposed to arsenic …

Damage to the genome is recognized as a fundamental cause of developmental and
degenerative diseases. Several micronutrients play an important role in protecting against …

The lack of toxicological information on many of the compounds that humans use or are
exposed to, intentionally or unintentionally, poses a big problem in risk assessment. To fill …

The increased frequency and intensity of short-term extreme warming phenomena have
been associated to harsh biological and ecosystem outcomes (ie, mass mortalities in marine …

Arsenic is one of the most toxic environmental toxicants. More than 150 million people
worldwide are exposed to arsenic through ground water contamination. It is an exclusive …

Accumulated evidence has shown that in vitro mammalian cell genotoxicity assays produce
high frequencies of “misleading” positive results, ie predicted hazard is not confirmed in in …

Arsenic (As) is a well documented human carcinogen. However, its mechanisms of toxic
action and carcinogenic potential in animals have not been conclusive. In this research, we …

Marine mussels can develop hemeic and gonadal neoplasia in the natural environment.
Associated with these diseases are the tumor suppressor (TS) p53 and the proto-oncogene …

Type 2 diabetes mellitus (T2D) is a metabolic disease, which occurs largely due to
unhealthy lifestyle. As oxidative stress is believed to promote T2D, by inducing damage to …