New developments in liposomal drug delivery

BS Pattni, VV Chupin, VP Torchilin - Chemical reviews, 2015 - ACS Publications
New Developments in Liposomal Drug Delivery | Chemical Reviews ACS ACS Publications
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Preparation, characterization and applications of liposomes: state of the art

A Laouini, C Jaafar-Maalej… - Journal of colloid …, 2012 - ingentaconnect.com
Liposomes, spherical-shaped nanovesicles, were discovered in the 60ies by Bangham.
Since that, they were extensively studied as potential drug carrier. Due to their composition …

Fluorescent analogs of biomolecular building blocks: design, properties, and applications

RW Sinkeldam, NJ Greco, Y Tor - Chemical reviews, 2010 - ACS Publications
Fluorescence spectroscopy, one of the most informative and sensitive analytical techniques,
has played and continues to play key roles in modern research. Indeed, unraveling the inner …

Bright ideas for chemical biology

LD Lavis, RT Raines - ACS chemical biology, 2008 - ACS Publications
Small-molecule fluorescent probes embody an essential facet of chemical biology. Although
numerous compounds are known, the ensemble of fluorescent probes is based on a modest …

Medium-chain lipid conjugation facilitates cell-permeability and bioactivity

J Morstein, A Capecchi, K Hinnah… - Journal of the …, 2022 - ACS Publications
The majority of bioactive molecules act on membrane proteins or intracellular targets and
therefore needs to partition into or cross biological membranes. Natural products often …

Rapid secretion of interleukin-1β by microvesicle shedding

A MacKenzie, HL Wilson, E Kiss-Toth, SK Dower… - Immunity, 2001 - cell.com
The proinflammatory cytokine interleukin-1β (IL-1β) is a secreted protein that lacks a signal
peptide and does not follow currently known pathways of secretion. Its efficient release from …

An antimicrobial peptide, magainin 2, induced rapid flip-flop of phospholipids coupled with pore formation and peptide translocation

K Matsuzaki, O Murase, N Fujii, K Miyajima - Biochemistry, 1996 - ACS Publications
The effect of an antimicrobial peptide, magainin 2, on the flip-flop rates of phospholipids was
investigated by use of fluorescent lipids, ie, anionic N-(7-nitrobenz-2-oxa-1, 3-diazol-4-yl) …

Fluorescence assay for phospholipid membrane asymmetry

JC McIntyre, RG Sleight - Biochemistry, 1991 - ACS Publications
Revised Manuscript Received September 19, 1991 abstract: Highly fluorescent 7-nitro-2, l, 3-
benzoxadiazol-4-yl-lipid (NBD-lipid) analogues are widely used to examine lipid …

Lysosome-targeted multifunctional lipid probes reveal the sterol transporter NPC1 as a sphingosine interactor

J Altuzar, J Notbohm, F Stein… - Proceedings of the …, 2023 - National Acad Sciences
Lysosomes are catabolic organelles involved in macromolecular digestion, and their
dysfunction is associated with pathologies ranging from lysosomal storage disorders to …

A novel fluorescent ceramide analogue for studying membrane traffic in animal cells: accumulation at the Golgi apparatus results in altered spectral properties of the …

RE Pagano, OC Martin, HC Kang… - The Journal of cell …, 1991 - rupress.org
A series of ceramide analogues bearing the fluorophore boron dipyrromethene difluoride
(BODIPY) were synthesized and evaluated as vital stains for the Golgi apparatus, and as …