Globally, human immunodeficiency virus type 1 (HIV-1) infection is a major health burden for
which successful therapeutic options are still being investigated. Challenges facing current …

Impressive therapeutic advances have been possible through the advent of zinc-finger
nucleases and transcription activator-like effector nucleases. However, discovery of the …

Gene editing techniques, which help in modification of any DNA sequence at ease, have
revolutionized the world of Genetic engineering. Although there are other gene-editing …

Human immunodeficiency virus (HIV) infection can be controlled by anti-retroviral therapy.
Suppressing viral replication relies on life-long medication, but anti-retroviral therapy is not …

Although tremendous efforts have been made to prevent and treat HIV-1 infection, HIV-
1/AIDS remains a major threat to global human health. The combination antiretroviral …

Introduction: The human immunodeficiency virus type 1 (HIV-1) pandemic has been slowed
with the advent of anti-retroviral therapy (ART). However, ART is not a cure and as such has …

The genetic background of Brazilians encompasses Amerindian, African, and European
components as a result of the colonization of an already Amerindian inhabited region by …

Viral infections can be fatal and consequently, they are a serious threat to human health.
Therefore, the development of vaccines and appropriate antiviral therapeutic agents is …

Although highly active antiretroviral therapy (HAART) can robustly control human
immunodeficiency virus (HIV) infection, the existence of latent HIV in a form of proviral DNA …

The onset of erythropoiesis is under strict developmental control, with direct and indirect
inputs influencing its derivation from the hematopoietic stem cell. A major regulator of this …