CDKN2A Gene Mutations: Implications for Hereditary Cancer Syndromes

A Danishevich, A Bilyalov, S Nikolaev, N Khalikov… - Biomedicines, 2023 - mdpi.com
Malignant neoplasms, including pancreatic cancer and melanoma, are major global health
challenges. This study investigates melanoma pancreatic syndrome, a rare hereditary tumor …

Association of a genetic variant in chromosome 9p21 with increased risk of developing cervical cancer

M Atabati, R Saber, P Malakuti… - Current Cancer …, 2023 - ingentaconnect.com
Background: Cervical cancer is one of the most prevalent gynecologic cancers associated
with high morbidity and mortality worldwide. There is mounting evidence indicating an …

[HTML][HTML] Association of a genetic variant in the cyclin-dependent kinase inhibitor 2B with risk of pancreatic cancer

N Sardarzadeh, F Khojasteh-Leylakoohi… - … of Biochemistry & …, 2022 - ncbi.nlm.nih.gov
Background: Pancreatic cancer (PC) is among the most aggressive tumors with a poor
prognosis, indicating the need for the identification of a novel prognostic biomarker for risk …

[HTML][HTML] Comprehensive analysis of cuproptosis-related genes involved in prognosis and tumor microenvironment infiltration of colorectal cancer

W Chen, K Hu, Y Liu, X Li, L Chen… - Translational Cancer …, 2024 - pmc.ncbi.nlm.nih.gov
Background Colorectal cancer (CRC) is a common malignancy, with high incidence and
high mortality rates. Cuproptosis, a novel form of copper-induced programmed cell death …

Evaluation of rs10811661 polymorphism in CDKN2A/B in colon and gastric cancer

M Beihaghi, R Sahebi, MR Beihaghi, RK Nessiani… - BMC cancer, 2023 - Springer
One of the causes of colon and gastric cancer is the dysregulation of carcinogenic genes,
tumor inhibitors, and micro-RNA. The purpose of this study is to apply rs10811661 …

[HTML][HTML] A Comprehensive Pan-Cancer Analysis Reveals Cyclin-Dependent Kinase Inhibitor 2A Gene as a Potential Diagnostic and Prognostic Biomarker in Colon …

A Salem, S Ahmed, M Khalfallah, N Hamadan… - Cureus, 2024 - ncbi.nlm.nih.gov
Methods We investigated CDKN2A gene expression in a pan-cancer analysis across
different types of cancer to show its diagnostic potential characteristics by using various …