Using biosensors to study organoids, spheroids and organs-on-a-chip: a mechanobiology perspective

MS Yousafzai, JA Hammer - Biosensors, 2023 - mdpi.com
The increasing popularity of 3D cell culture models is being driven by the demand for more
in vivo-like conditions with which to study the biochemistry and biomechanics of numerous …

Extracellular matrix as a driver of Chronic Lung diseases

JK Burgess, DJ Weiss… - American Journal of …, 2024 - atsjournals.org
The extracellular matrix (ECM) is not just a three-dimensional scaffold that provides stable
support for all cells in the lungs, but also an important component of chronic fibrotic airway …

[HTML][HTML] ECM-mimicking composite hydrogel for accelerated vascularized bone regeneration

G Li, F Gao, D Yang, L Lin, W Yu, J Tang, R Yang… - Bioactive Materials, 2024 - Elsevier
Bioactive hydrogel materials have great potential for applications in bone tissue
engineering. However, fabrication of functional hydrogels that mimic the natural bone …

Rapidly Degrading Hydrogels to Support Biofabrication and 3D Bioprinting Using Cartilage Microtissues

GS Kronemberger, FD Spagnuolo… - ACS Biomaterials …, 2024 - ACS Publications
In recent years, there has been increased interest in the use of cellular spheroids,
microtissues, and organoids as biological building blocks to engineer functional tissues and …

[HTML][HTML] Xyloglucan, alginate and k-carrageenan hydrogels on spheroids of adipose stem cells survival; preparation, mechanical characterization, morphological …

E Muscolino, AB Di Stefano, F Toia… - Carbohydrate Polymer …, 2024 - Elsevier
The therapeutic capabilities of autologous stem cells can be fully exploited if their survival
after implantation is improved. For the first time, we compared three hydrogels, with different …

[HTML][HTML] Structuring supramolecular hyaluronan hydrogels via peptide self-assembly for modulating the cell microenvironment

Y Yuan, Y Shi, J Banerjee, A Sadeghpour… - Materials Today Bio, 2023 - Elsevier
The use of synthetic extracellular matrices (ECMs) in fundamental in vitro cell culture studies
has been instrumental for investigating the interplay between cells and matrix components …

The future of cell-instructive biomaterials for tissue regeneration–a perspective from early career clinician-scientists

R Rangel, WB Swanson, DT Wu - Frontiers in Materials, 2024 - frontiersin.org
Cell-instructive biomaterials are an essential component in tissue engineering and
regenerative medicine. In the past three decades since the term “Tissue Engineering” was …

Mechanobiology-informed biomaterial and tissue engineering strategies for influencing skeletal stem and progenitor cell fate

SM Woodbury, WB Swanson, Y Mishina - Frontiers in Physiology, 2023 - frontiersin.org
Skeletal stem and progenitor cells (SSPCs) are the multi-potent, self-renewing cell lineages
that form the hematopoietic environment and adventitial structures of the skeletal tissues …

Designing highly tunable nanostructured peptide hydrogels using differential thermal histories to achieve variable cellular responses

S Sen, S Mohanty, S Roy - Nanoscale, 2025 - pubs.rsc.org
In this study, we demonstrate a unique and promising approach to access peptide-based
diverse nanostructures in a single gelator regime that is capable of exhibiting different …

Extracellular matrix mimetic supramolecular hydrogels reinforced with covalent crosslinked mesoporous silica nanoparticles

A Zengin, S Hafeez, P Habibovic, M Baker… - Journal of Materials …, 2024 - pubs.rsc.org
The extracellular matrix (ECM) is a dynamic environment that is primarily built up from
fibrous proteins (eg, elastins, fibronectins, collagens, and laminins) and plays a vital role in …