Nanotechnology, as an emerging science, has taken over all fields of life including
industries, health and medicine, environmental issues, agriculture, biotechnology etc. The …

There are several routes of administration to the brain, including intraparenchymal,
intraventricular, and subarachnoid injections. The blood-brain barrier (BBB) impedes the …

The goal of nanomedicine is to address specific clinical problems optimally, to fight human
diseases, and to find clinical relevance to change clinical practice. Nanomedicine is poised …

This review concerns the use of dendrimers, especially of phosphorhydrazone dendrimers,
against cancers. After the introduction, the review is organized in three main topics …

TNF-related apoptosis-inducing ligand (TRAIL), a member of the TNF superfamily, can
induce apoptosis in cancer cells, sparing normal cells when bound to its associated death …

Cancer treatment with small interfering RNA (siRNA) is one of the most promising new
strategies; however, transfection systems that increase its bioavailability and ensure its …

Two families of phosphorhydrazone dendrons having either an azide or an alkyne linked to
the core and diverse types of pyridine derivatives as terminal functions have been …

Metallopolymers (MPs) or metal-containing polymers have shown great potential as new
drug delivery systems (DDSs) due to their unique properties, including universal …

Dendritic cells (DCs) are asserted as the most potent antigen-presenting cells (APCs) that
orchestrate both innate and adaptive immunity, being extremely effective in the induction of …

Dendritic molecules bearing metal complexes in their structure (metallodendrimers and
metallodendrons) are considered prospective therapeutic entities. In particular …