Olfactory immunology: the missing piece in airway and CNS defence

SA Wellford, EA Moseman - Nature Reviews Immunology, 2024 - nature.com
The olfactory mucosa is a component of the nasal airway that mediates the sense of smell.
Recent studies point to an important role for the olfactory mucosa as a barrier to both …

Current status and progress in stem cell therapy for intracerebral hemorrhage

N Ding, R Luo, Q Zhang, H Li, S Zhang, H Chen… - Translational Stroke …, 2023 - Springer
Intracerebral hemorrhage is a highly prevalent and prognostically poor disease, imposing
immeasurable harm on human life and health. However, the treatment options for …

[HTML][HTML] Effect of valproic acid combined with transplantation of olfactory ensheathing cells modified by neurotrophic 3 gene on nerve protection and repair after …

H Li, Z Yin, S Yue, Y An, X Wang, S Zhou, L Meng… - Neuropeptides, 2024 - Elsevier
Background Traumatic brain injury (TBI) often leads to cognitive and neurological
dysfunction. Valproic acid (VPA) has a neuroprotective effect in acute central nervous …

Transplantation of Cryopreserved Olfactory Ensheathing Cells Restores Loss of Functions in an Experimental Model

K Minkelyte, D Li, Y Li, A Ibrahim - Cell Transplantation, 2023 - journals.sagepub.com
In the past decades, the properties of olfactory ensheathing cells (OECs) have been widely
investigated. Studies have shown that transplantation of OECs cultured from the olfactory …

[HTML][HTML] Therapeutic Potential of Olfactory Ensheathing Cells and Adipose-Derived Stem Cells in Osteoarthritis: Insights from Preclinical Studies

YH Chang, KC Wu, CJ Hsu, TC Tu, MC Liu… - Cells, 2024 - mdpi.com
Olfactory-ensheathing cells (OECs) are known for their role in neuronal regeneration and
potential to promote tissue repair. Adipose-derived stem cells (ADSCs), characterized by …

[HTML][HTML] Melatonin Enhances Neural Differentiation of Adipose-Derived Mesenchymal Stem Cells

IR Romano, F D'Angeli, E Gili, M Fruciano… - International Journal of …, 2024 - mdpi.com
Adipose-derived mesenchymal stem cells (ASCs) are adult multipotent stem cells, able to
differentiate toward neural elements other than cells of mesodermal lineage. The aim of this …

Application and challenges of olfactory ensheathing cells in clinical trials of spinal cord injury

H Huang, M Xiong, F Pu, J Liao, F Zhu… - European Journal of …, 2023 - Elsevier
Spinal cord injury (SCI) can lead to severe motor, sensory and autonomic nervous
dysfunction, cause serious psychosomatic injury to patients. There is no effective treatment …

Sigma-1 receptor targeting inhibits connexin 43 based intercellular communication in chronic neuropathic pain

S Denaro, S D'Aprile, F Torrisi, A Zappalà… - Inflammation …, 2024 - Springer
Background and objective Neuropathic pain is a chronic condition characterized by aberrant
signaling within the somatosensory system, affecting millions of people worldwide with …

The role of olfactory ensheathing cells in the repair of nerve injury

J Liao, F Zhu, Y Liu, S Liu, Z Liu, W Zhang - European Journal of …, 2024 - Elsevier
Cell transplantation has brought about a breakthrough in the treatment of nerve injuries, and
the efficacy of cell transplantation compared to drug and surgical therapies is very exciting …

Co-Administration of Resolvin D1 and Peripheral Nerve-Derived Stem Cell Spheroids as a Therapeutic Strategy in a Rat Model of Spinal Cord Injury

SY Jeong, HL Lee, SW Wee, HY Lee… - International Journal of …, 2023 - mdpi.com
Spinal cord injury (SCI), primarily caused by trauma, leads to permanent and lasting loss of
motor, sensory, and autonomic functions. Current therapeutic strategies are focused on …