Ionising radiation stands as an indispensable protagonist in the narrative of medical
imaging, underpinning diagnostic evaluations and therapeutic interventions across an array …

The cornerstones of science advancement are rigor in performing scientific research,
reproducibility of research findings and unbiased reporting of design and results of the …

The goal of this study was to establish a model of partial-body irradiation (PBI) sparing 2.5%
of the bone marrow (BM2. 5-PBI) that accurately recapitulates radiological/nuclear exposure …

Purpose Natural history studies have been informative in dissecting radiation injury,
isolating its effects, and compartmentalizing injury based on the extent of exposure and the …

Background Genetically engineered mouse models (GEMMs) of cancer are powerful tools to
study mechanisms of disease progression and therapy response, yet little is known about …

Preclinical researchers have long acknowledged the critical need for accurate dosimetry in
the conduct of radiation-exposure studies involving living systems. Although radiation …

Abstract Radionuclide irradiators (137Cs and 60Co) are commonly used in preclinical
studies ranging from cancer therapy to stem cell biology. Amidst concerns of radiological …

Validation of biodosimetry assays is routinely performed using primarily orthovoltage
irradiators at a conventional dose rate of approximately 1 Gy/min. However …

The clinical importance of radiotherapy in the treatment of cancer patients justifies the
development and use of research tools at the fundamental, pre-clinical, and ultimately …

Interventional radiology has grown considerably over the last decades and become an
essential tool for treatment or diagnosis. This technique is mostly beneficial and mastered …