Gold nanoparticles and gold nanorods in the landscape of cancer therapy

P Kesharwani, R Ma, L Sang, M Fatima, A Sheikh… - Molecular cancer, 2023 - Springer
Cancer is a grievous disease whose treatment requires a more efficient, non-invasive
therapy, associated with minimal side effects. Gold nanoparticles possessing greatly …

Hereditary prostate cancer: genes related, target therapy and prevention

MT Vietri, G D'elia, G Caliendo, M Resse… - International journal of …, 2021 - mdpi.com
Prostate cancer (PCa) is globally the second most diagnosed cancer type and the most
common cause of cancer-related deaths in men. Family history of PCa, hereditary breast …

Gene expression based inference of cancer drug sensitivity

S Chawla, A Rockstroh, M Lehman, E Ratther… - Nature …, 2022 - nature.com
Inter and intra-tumoral heterogeneity are major stumbling blocks in the treatment of cancer
and are responsible for imparting differential drug responses in cancer patients. Recently …

Palmitic acid inhibits prostate cancer cell proliferation and metastasis by suppressing the PI3K/Akt pathway

S Zhu, W Jiao, Y Xu, L Hou, H Li, J Shao, X Zhang… - Life Sciences, 2021 - Elsevier
Aims Prostate cancer is one of the most frequent causes of cancer death in men worldwide,
and novel drugs for prostate cancer therapies are still being developed. Palmitic acid is a …

Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states

H Song, HNW Weinstein, P Allegakoen… - Nature …, 2022 - nature.com
Prostate cancer is the second most common malignancy in men worldwide and consists of a
mixture of tumor and non-tumor cell types. To characterize the prostate cancer tumor …

The promising role of new molecular biomarkers in prostate cancer: From coding and non-coding genes to artificial intelligence approaches

AP Alarcón-Zendejas, A Scavuzzo… - Prostate cancer and …, 2022 - nature.com
Background Risk stratification or progression in prostate cancer is performed with the
support of clinical-pathological data such as the sum of the Gleason score and serum levels …

Cytokines and chemokines as mediators of prostate cancer metastasis

TO Adekoya, RM Richardson - International journal of molecular sciences, 2020 - mdpi.com
The consequences of prostate cancer metastasis remain severe, with huge impact on the
mortality and overall quality of life of affected patients. Despite the convoluted interplay and …

Resistance to second-generation androgen receptor antagonists in prostate cancer

KT Schmidt, ADR Huitema, CH Chau… - Nature Reviews …, 2021 - nature.com
The introduction of second-generation androgen receptor antagonists (SG-ARAs) has
greatly impacted the treatment of metastatic prostate cancer, providing tolerable and …

Transcriptional mediators of treatment resistance in lethal prostate cancer

MX He, MS Cuoco, J Crowdis, A Bosma-Moody… - Nature medicine, 2021 - nature.com
Metastatic castration-resistant prostate cancer is typically lethal, exhibiting intrinsic or
acquired resistance to second-generation androgen-targeting therapies and minimal …

Role of small molecule targeted compounds in cancer: progress, opportunities, and challenges

G Sun, D Rong, Z Li, G Sun, F Wu, X Li… - Frontiers in cell and …, 2021 - frontiersin.org
Research on molecular targeted therapy of tumors is booming, and novel targeted therapy
drugs are constantly emerging. Small molecule targeted compounds, novel targeted therapy …