The prevalence of nitrogen containing heterocycles in natural products and pharmaceuticals
is a doubtless fact. In this review, recent applications of a stereoselective aza-Michael …

Catalytic asymmetric N‐alkylation of indoles and carbazoles represents a family of important
but underdeveloped reactions. Herein, we describe a new organocatalytic strategy in which …

During the past two decades, the interest in new methodologies for the synthesis of chiral N-
functionalized indoles has grown rapidly. The review illustrates efficient applications of …

Catalytic asymmetric functionalization of the N–H groups of indoles and carbazoles
constitutes an important but less developed class of reactions. Herein, we describe a …

A new ruthenium-based catalytic system for branched-selective asymmetric allylic alkylation
is disclosed and applied to the synthesis of chiral isatin derivatives. The catalyst, which is …

A method of SPINOL-derived chiral phosphoric acid catalyzed asymmetric intermolecular N-
hydroxyalkylation of multisubstituted indoles with ethyl glyoxalates is described in this report …

A chemo‐and enantioselective protocol for the N‐alkylation of indoles with imines was
developed. This process was catalyzed by a BINOL‐derived phosphoric acid catalyst to give …

Several chiral BINOL‐derived bisoxazoline (BOX)/copper (II) complexes were synthesized
and evaluated as catalysts for the Friedel–Crafts reaction of indoles with isatin‐derived β, γ …

A catalytic enantioselective hydroxyamination of α, β-unsaturated 2-acyl imidazoles with N-
protected hydroxyl amines catalyzed by a chiral-at-metal Rh (III) complex (0.5–2 mol%) has …

The partitioned n-hexane, CHCl3, and EtOAc extracts from the crude MeOH extract of
Phaius mishmensis showed considerable cytotoxicities against the human breast carcinoma …