Every cell in nature carries a rich surface coat of glycans, its glycocalyx, which constitutes
the cell's interface with its environment. In eukaryotes, the glycocalyx is composed of …

Polysialic acid (PSA), a homopolymer attached to the neural cell adhesion molecule
(NCAM), serves as a modulator of cell interactions. Polysialic acid exhibits a highly …

Inactivation of the mouse homologue of the Huntington disease gene (Hdh) results in early
embryonic lethality. To investigate the normal function of Hdh in the adult and to evaluate …

Monoclonal antibody 6F8 was used to characterize and clone fasciclin IV, a new axonal
glycoprotein in the grasshopper, and to study its function during growth cone guidance …

N-CAM is abundantly expressed in the nervous system in the form of numerous structural
variants with characteristic distribution patterns and functional properties. N-CAM-180, the …

By combining both immunocytochemical and functional investigations, a hypothetical
framework will be developed for the molecular mechanisms underlying neuron-glia …

A locus for X–linked hydrocephalus (HSAS), which is characterized by mental retardation
and enlarged brain ventricles, maps to the same subchromosomal region (Xq28) as the …

There is increasing evidence that target-derived molecules play a crucial role in the
regulation of neuronal survival during development. These molecules, termed neurotrophic …

The neural cell adhesion molecule (NCAM), probably the best characterized and most
abundant cell adhesion molecule on neurons, is thought to be a major regulator of axonal …

Immunoglobulin/fibronectin type Ill-like cell adhesion molecules have been implicated in
axon pathfinding based on their expression pattern in the developing nervous system and …