Though the cause of cystic fibrosis (CF) pathology is understood to be the mutation of the
CFTR protein, it has been difficult to trace the exact mechanisms by which the pathology …

The cystic fibrosis transmembrane regulator (CFTR) should no longer be viewed primarily as
a 'chloride channel'but recognized as a channel that also controls the efflux of other …

Diisocyanatotoluene (toluene diisocyanate, TDI), a 4: 1 mixture of 2, 4-and 2, 6-isomers
used in the preparation of polyurethanes, causes occupational asthma by an as yet …

γ-Glutamyltranspeptidase (GGT)-deficient mice (GGT−/−) display chronic glutathione (GSH)
deficiency, growth retardation, and die at a young age (< 20 weeks). Using livers from these …

The protective effects of glutathione monoester (GME) on buthionine sulfoximine (BSO)-
induced glutathione (GSH) depletion and its sequel were evaluated in rat …

Administration of acrolein (2.5 mg/kg body weight/day) to rats for 45 days depleted the
glutathione level in liver, which triggered an imbalance in the antioxidant defense, resulting …

The effect of glutathione monoester (GME) on buthionine sulfoximine (BSO) mediated
glutathione (GSH) depletion in rats was studied to understand the defensive role of …

Antioxidant therapy can improve the protection and metabolic activity of cells and tissues. In
this study, the effect of vitamin E administration on buthionine sulfoximine (BSO)‐induced …

Eukaryotic cells possess distinct and double-membrane encapsulated organelles, the
mitochondria. The mitochondrion is the powerhouse of the cell responsible for energy …

Que Dª. Mª Elena Rodríguez García, Licenciada en Biología por la Universidad
Complutense de Madrid, ha realizado bajo mi dirección el trabajo correspondiente a su …