Heart transplantation: focus on donor recovery strategies, left ventricular assist devices, and novel therapies

MG Crespo-Leiro, MR Costanzo… - European heart …, 2022 - academic.oup.com
Heart transplantation is advocated in selected patients with advanced heart failure in the
absence of contraindications. Principal challenges in heart transplantation centre around an …

Heart transplantation: advances in expanding the donor pool and xenotransplantation

S Jou, SR Mendez, J Feinman, LR Mitrani… - Nature Reviews …, 2024 - nature.com
Approximately 65 million adults globally have heart failure, and the prevalence is expected
to increase substantially with ageing populations. Despite advances in pharmacological and …

WITHDRAWN: Executive Summary-The International Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients

A Velleca, MA Shullo, K Dhital, E Azeka, M Colvin… - 2022 - Elsevier
WITHDRAWN: Executive Summary - The International Society for Heart and Lung
Transplantation (ISHLT) guidelines for the care of heart transplant recipients - ScienceDirect Skip …

Transplantation outcomes with donor hearts after circulatory death

JN Schroder, CB Patel, AD Devore… - … England Journal of …, 2023 - Mass Medical Soc
Background Data showing the efficacy and safety of the transplantation of hearts obtained
from donors after circulatory death as compared with hearts obtained from donors after brain …

[HTML][HTML] A 5-year single-center early experience of heart transplantation from donation after circulatory-determined death donors

S Messer, S Cernic, A Page, M Berman, P Kaul… - The Journal of Heart and …, 2020 - Elsevier
BACKGROUND In an effort to address the increasing demand for heart transplantation
within the United Kingdom (UK), we established a clinical program of heart transplantation …

Expanding controlled donation after the circulatory determination of death: statement from an international collaborative

B Domínguez-Gil, N Ascher, AM Capron… - Intensive care …, 2021 - Springer
A decision to withdraw life-sustaining treatment (WLST) is derived by a conclusion that
further treatment will not enable a patient to survive or will not produce a functional outcome …

Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation

JL Martin, ASH Costa, AV Gruszczyk, TE Beach… - Nature …, 2019 - nature.com
During heart transplantation, storage in cold preservation solution is thought to protect the
organ by slowing metabolism, providing osmotic support and minimizing ischaemia …

[HTML][HTML] Early experience with donation after circulatory death heart transplantation using normothermic regional perfusion in the United States

DE Smith, ZN Kon, JA Carillo, S Chen, CG Gidea… - The Journal of Thoracic …, 2022 - Elsevier
Objective This pilot study sought to evaluate the feasibility of our donation after circulatory
death (DCD) heart transplantation protocol using cardiopulmonary bypass (CPB) for …

Feasibility and potential impact of heart transplantation from adult donors after circulatory death

S Madan, O Saeed, SJ Forest, DJ Goldstein… - Journal of the American …, 2022 - jacc.org
Background A shortage of donation after brain death (DBD) donors for heart transplantation
(HT) persists. Recent improvements in organ procurement from donation after circulatory …

Therapeutic inhibition of acid-sensing ion channel 1a recovers heart function after ischemia–reperfusion injury

MA Redd, SE Scheuer, NJ Saez, Y Yoshikawa… - Circulation, 2021 - Am Heart Assoc
Background: Ischemia–reperfusion injury (IRI) is one of the major risk factors implicated in
morbidity and mortality associated with cardiovascular disease. During cardiac ischemia, the …